| Gene Symbol |
NDUFA1
|
| Entrez Gene |
4694
|
| Alt Symbol |
CI-MWFE, MWFE, ZNF183
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
|
| Other Description |
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1|NADH oxidoreductase subunit MWFE|NADH-ubiquinone oxidoreductase MWFE subunit|NADH:ubiquinone oxidoreductase (complex 1)|complex I MWFE subunit|complex I-MWFE|type I dehydrogenase
|
| Swissprots |
O15239
|
| Accessions |
EAW89840 O15239 AB451304 BAG70118 AB451435 BAG70249 BC000266 AAH00266 BQ680674 CR456889 CAG33170 U54993 AAD00084 X81900 CAA57489 NM_004541 NP_004532
|
| Function |
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
|
| Subcellular Location |
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
|
| Tissue Specificity |
Primarily expressed in heart and skeletal muscle.
|
| Top Pathways |
Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation
|