Gene Symbol | NDUFA1 |
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Entrez Gene | 4694 |
Alt Symbol | CI-MWFE, MWFE, ZNF183 |
Species | Human |
Gene Type | protein-coding |
Description | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa |
Other Description | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1|NADH oxidoreductase subunit MWFE|NADH-ubiquinone oxidoreductase MWFE subunit|NADH:ubiquinone oxidoreductase (complex 1)|complex I MWFE subunit|complex I-MWFE|type I dehydrogenase |
Swissprots | O15239 |
Accessions | EAW89840 O15239 AB451304 BAG70118 AB451435 BAG70249 BC000266 AAH00266 BQ680674 CR456889 CAG33170 U54993 AAD00084 X81900 CAA57489 NM_004541 NP_004532 |
Function | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
Subcellular Location | Mitochondrion inner membrane; Single-pass membrane protein; Matrix side. |
Tissue Specificity | Primarily expressed in heart and skeletal muscle. |
Top Pathways | Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |
NDUFA1 CRISPR/Cas9 KO Plasmid (h) - sc-409185 from Santa Cruz Biotechnology
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NDUFA1 HDR Plasmid (h) - sc-409185-HDR from Santa Cruz Biotechnology
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NDUFA1 Double Nickase Plasmid (h) - sc-409185-NIC from Santa Cruz Biotechnology
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NDUFA1 Double Nickase Plasmid (h2) - sc-409185-NIC-2 from Santa Cruz Biotechnology
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NDUFA1 CRISPR Activation Plasmid (h) - sc-409185-ACT from Santa Cruz Biotechnology
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NDUFA1 CRISPR Activation Plasmid (h2) - sc-409185-ACT-2 from Santa Cruz Biotechnology
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NDUFA1 Lentiviral Activation Particles (h) - sc-409185-LAC from Santa Cruz Biotechnology
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NDUFA1 Lentiviral Activation Particles (h2) - sc-409185-LAC-2 from Santa Cruz Biotechnology
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NDUFA1 siRNA (h) - sc-90892 from Santa Cruz Biotechnology
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NDUFA1 shRNA Plasmid (h) - sc-90892-SH from Santa Cruz Biotechnology
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NDUFA1 shRNA (h) Lentiviral Particles - sc-90892-V from Santa Cruz Biotechnology
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NDUFA1 RNAi - H00004694-R01 from Novus Biologicals
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MISSION® esiRNA - EHU040351 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15134 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15134 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00184 from Sigma-Aldrich
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NDUFA1 siRNA (Human) - CRH3109 from Cohesion Biosciences
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shRNA set against Human NDUFA1 (NM_004541.3) - SHH350460 from Creative biogene
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shRNA set against Human NDUFA1(NM_004541.3) - SHR004576 from Creative biogene
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Human NDUFA1 siRNA - orb263611 from Biorbyt
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NDUFA1 shRNA Plasmid (Human) - CHH3109 from Cohesion Biosciences
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NDUFA1 miRNA 3'UTR clone - MiUTR1H-06695 from Creative biogene
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