Gene Symbol | NUDC |
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Entrez Gene | 10726 |
Alt Symbol | HNUDC, MNUDC, NPD011 |
Species | Human |
Gene Type | protein-coding |
Description | nudC nuclear distribution protein |
Other Description | nuclear distribution C homolog|nuclear distribution gene C homolog|nuclear distribution protein C homolog|nuclear migration protein nudC |
Swissprots | Q9Y266 Q9H0N2 Q9Y2B6 Q5QP31 Q5QP35 |
Accessions | EAX07780 Q9Y266 AB019408 BAA76628 AF086922 AAP97152 AF100760 AAD43024 AF125465 AAD39921 AF130736 AAD30517 AF241788 AAG44476 AL136725 CAB66659 AM392722 CAL37600 AM393251 CAL38129 BC002399 AAH02399 BC003132 AAH03132 BC006147 AAH06147 BC007280 AAH07280 BC015153 AAH15153 BC021139 AAH21139 BP348144 XM_011540529 XP_011538831 XM_011540530 XP_011538832 NM_006600 NP_006591 |
Function | Plays a role in neurogenesis and neuronal migration (By similarity). Necessary for correct formation of mitotic spindles and chromosome separation during mitosis. Necessary for cytokinesis and cell proliferation. {ECO:0000250, ECO:0000269|PubMed:12679384, ECO:0000269|PubMed:12852857}. |
Subcellular Location | Cytoplasm, cytoskeleton. Nucleus. Note=In a filamentous pattern adjacent to the nucleus of migrating cerebellar granule cells. Colocalizes with tubulin and dynein and with the microtubule organizing center. Distributed throughout the cytoplasm of non-migrating cells. A small proportion is nuclear, in a punctate pattern. |
Tissue Specificity | Ubiquitous. Highly expressed in fetal liver, kidney, lung and brain. Highly expressed in adult pancreas, kidney, skeletal muscle, liver, lung, placenta, prostate, brain and heart. {ECO:0000269|PubMed:10210332, ECO:0000269|PubMed:10453739}. |
Human NUDC full length protein - ab153119 from Abcam
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Human NUDC full length protein - ab153120 from Abcam
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NUDC Antibody Blocking Peptide - LS-E3873 from LifeSpan Bioscience
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NUDC Antibody Blocking Peptide - LS-E27126 from LifeSpan Bioscience
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NUDC Antibody Blocking Peptide - LS-E18751 from LifeSpan Bioscience
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NUDC Recombinant Protein - H00010726-P01 from Novus Biologicals
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NUDC Recombinant Protein - H00010726-P02 from Novus Biologicals
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NUDC-Antibody-Center-Blocking-Peptide - BP16056c from Abgent, a WuXi AppTec company
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NUDC blocking peptide - GTX88334-PEP from GeneTex
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Human NUDC (His Tag) protein - orb232348 from Biorbyt
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NUDC Blocking Peptide - 33R-1848 from Fitzgerald
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NUDC Peptide - AC21-1945-P from Abcore
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NUDC - H00010726-P01-10 from Acris Antibodies
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NUDC - H00010726-P01-25 from Acris Antibodies
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NUDC - H00010726-P02 from Acris Antibodies
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NUDC - H00010726-P02-10 from Acris Antibodies
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NUDC - H00010726-P02-25 from Acris Antibodies
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NUDC Peptide - 42-108P from ProSci
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NUDC fusion protein - ag0998 from Proteintech Group
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Recombinant Nuclear Distribution Gene C Homolog (NUDC) - RPJ712Hu01 from Uscn Life Science Inc.
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Human NUDC Protein (His Tag) - 15068-H08H-20 from Sino Biological
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Recombinant Nuclear Distribution Gene C Homolog (NUDC) - RPJ712Hu01 from Cloud-clone
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NUDC - TP303543 from Acris Antibodies
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NUDC, Peptide - MBS426108 from MyBioSource
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Recombinant Human NUDC Protein, His-tagged - NUDC-645H from Creative Biomart
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