| Gene Symbol |
ZHX3
|
| Entrez Gene |
23051
|
| Alt Symbol |
TIX1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
zinc fingers and homeoboxes 3
|
| Other Description |
triple homeobox 1|triple homeobox protein 1|zinc finger and homeodomain protein 3|zinc fingers and homeoboxes protein 3
|
| Swissprots |
Q6NUJ7 F5H820 O43145 E1P5W5 Q9H4I2
|
| Accessions |
EAW75987 EAW75988 Q9H4I2 AB007855 BAA23691 AB081948 BAC65211 AI754653 AK090560 AK097523 AK122905 AK292415 BAF85104 AW502552 BC020258 BC047070 BC068569 AAH68569 BI458686 BM905948 BM980061 DQ583641 DQ586571 DQ599687 XM_005260341 XP_005260398 XM_005260343 XP_005260400 XM_006723747 XP_006723810 XM_006723748 XP_006723811 XM_006723749 XP_006723812 XM_011528701 XP_011527003 XM_011528702 XP_011527004 XM_011528703 XP_011527005 XM_011528704 XP_011527006 XM_011528705 XP_011527007 XM_011528706 XP_011527008 XM_011528707 XP_011527009 XM_011528708 XP_011527010 XM_011528709 XP_011527011 XM_011528710 XP_011527012 XM_011528711 XP_011527013 XM_011528712 XP_011527014 XM_011528713 XP_011527015 XM_011528714 XP_011527016 XM_011528715 XP_011527017 XM_011528716 XP_011527018 XM_011528717 XP_011527019 XM_011528718 XP_011527020 XM_011528719 XP_011527021 XM_011528720 XP_011527022 NM_015035 NP_055850
|
| Function |
Acts as a transcriptional repressor. Involved in the early stages of mesenchymal stem cell (MSC) osteogenic differentiation. Is a regulator of podocyte gene expression during primary glomerula disease. Binds to promoter DNA. {ECO:0000269|PubMed:12659632, ECO:0000269|PubMed:21174497}.
|
| Subcellular Location |
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000269|PubMed:12659632}.
|
| Tissue Specificity |
Widely expressed. High expression in kidney. Expressed during osteogenic differentiation. {ECO:0000269|PubMed:12659632, ECO:0000269|PubMed:21174497}.
|
