Gene Symbol | AP1B1 |
---|---|
Entrez Gene | 162 |
Alt Symbol | ADTB1, AP105A, BAM22, CLAPB2 |
Species | Human |
Gene Type | protein-coding |
Description | adaptor-related protein complex 1, beta 1 subunit |
Other Description | AP-1 complex subunit beta-1|Golgi adaptor HA1/AP1 adaptin beta subunit|adapter-related protein complex 1 subunit beta-1|adaptor protein complex AP-1 subunit beta-1|adaptor-related protein complex 1 subunit beta-1|beta-1-adaptin|beta-adaptin 1|beta-prime-adaptin|beta1-adaptin|clathrin assembly protein complex 1 beta large chain|plasma membrane adaptor HA2/AP2 adaptor beta subunit |
Swissprots | Q86X54 Q20WL3 P78436 F8WDL0 C9JRD1 Q10567 |
Accessions | AAC50684 CBF79614 CBU99115 EAW59798 EAW59799 EAW59800 Q10567 AI084003 AK294406 BAG57658 AK296567 BAG59187 AK299613 BAG61541 AU139022 BC046242 AAH46242 BG999878 BM909530 BX537680 CAD97809 CD364485 CT841508 CAJ86438 CU012936 CAK54367 CU013224 CAK54666 L13939 AAC98702 NM_001127 NP_001118 NM_001166019 NP_001159491 NM_145730 NP_663782 |
Function | Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. |
Subcellular Location | Golgi apparatus. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex. |
Tissue Specificity | Widely expressed. |
Top Pathways | Lysosome |