PPP2R2B

Gene Symbol PPP2R2B
Entrez Gene 5521
Alt Symbol B55BETA, PP2AB55BETA, PP2ABBETA, PP2APR55B, PP2APR55BETA, PR2AB55BETA, PR2ABBETA, PR2APR55BETA, PR52B, PR55-BETA, PR55BETA, SCA12
Species Human
Gene Type protein-coding
Description protein phosphatase 2, regulatory subunit B, beta
Other Description PP2A subunit B isoform B55-beta|PP2A subunit B isoform PR55-beta|PP2A subunit B isoform R2-beta|PP2A, subunit B, B-beta isoform|protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform|protein phosphatase 2 (formerly 2A), regulatory subunit B, beta isoform|serine/threonine protein phosphatase 2A, 55 kDa regulatory subunit B, beta isoform|serine/threonine protein phosphatase 2A, neuronal isoform|serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform
Swissprots D3DQF8 B7Z304 D3DQF7 A6NEJ2 A8K102 Q00005 B7Z2F2 B3KPD0 G3V149
Accessions AAF74024 EAW61829 EAW61830 EAW61831 EAW61832 EAW61833 EAW61834 EAW61835 Q00005 AI621232 AK056192 BAG51642 AK289717 BAF82406 AK294659 BAH11838 AK295347 BAH12040 AK314810 AL540315 AV726282 BC031790 AAH31790 BI669304 BP195204 BX464346 BX647887 DA155307 DA158596 DA365141 DA522334 DA523686 DA533318 DQ891785 ABM82711 DQ894969 ABM85895 M64930 AAA36491 NM_001271899 NP_001258828 NM_001271900 NP_001258829 NM_001271948 NP_001258877 NM_181674 NP_858060 NM_181675 NP_858061 NM_181676 NP_858062 NM_181677 NP_858063 NM_181678 NP_858064 NR_073526 NR_073527
Function The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Within the PP2A holoenzyme complex, isoform 2 is required to promote proapoptotic activity (By similarity). Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance (By similarity). {ECO:0000250}.
Subcellular Location Isoform 1: Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Membrane {ECO:0000250}.
Tissue Specificity Brain.
Top Pathways Dopaminergic synapse, mRNA surveillance pathway, PI3K-Akt signaling pathway, Hepatitis C, Hippo signaling pathway

Anti-PPP2R2B antibody - ab16447 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PPP2R2B antibody - ab93131 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-PPP2R2B antibody (ab93131) at 1/100 dilution + Hela cell line lysate at 35 µg

Anti-PPP2R2B antibody - ab58152 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab58152 PPP2R2B antibody at 1ug/ml.

Anti-PPP2R2B antibody [EPR10961] - ab157461 from Abcam

Prices $99.00, $379.00
Sizes 10 µl, 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR10961
All lanes : Anti-PPP2R2B antibody [EPR10961] (ab157461) at 1/1000 dilutionLane 1 : HepG2 cell lysateLane 2 : SH-SY5Y cell lysateLane 3 : Jurkat cell lysateLane 4 : HeLa cell lysateLane 5 : Human fetal brain lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-PPP2R2B Antibody (aa2-14) - LS-C26541 from LifeSpan Bioscience

Prices $330.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PPP2R2B Antibody (Internal, AP) - LS-C281521 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPP2R2B Antibody (Internal, APC) - LS-C281522 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPP2R2B Antibody (Internal, Biotin) - LS-C281523 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPP2R2B Antibody (clone 1B10) - LS-C139142 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1B10
Immunoprecipitation of PPP2R2B transfected lysate using anti-PPP2R2B monoclonal antibody and Protein A Magnetic Bead.

Anti-PPP2R2B Antibody (Internal, FITC) - LS-C281525 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPP2R2B Antibody (Internal, Azide-free, HRP) - LS-C281526 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPP2R2B Antibody (Internal, PE) - LS-C281527 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPP2R2B Antibody (Internal) - LS-C328373 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPP2R2B Antibody (clone 1F3) IHC-plus™ - LS-B6417 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 1F3
Anti-PPP2R2B antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6417 concentration 5 ug/ml.

Anti-PPP2R2B Antibody (aa25-75) - LS-C287796 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human and Mouse PPP2R2B by WB (h&m) and Immunoprecipitation (h). Samples: Whole cell lysate from HeLa (5, 15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded), 293T (T; 50 ug) and mouse NIH3T3 (M; 50 ug) cells. Antibodies: Affinity purified rabbit anti-PPP2R2B antibody used for WB at 0.1 ug/ml (A) and 1 ug/ml (B) and used for IP at 3 ug/mg lysate (B). Detection: Chemiluminescence with exposure times of 3 minutes (A) and 30 seconds (B).

Anti-PPP2R2B Antibody (aa104-130) - LS-C162087 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human brain tissue with PPP2R2B Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

PPP2R2B Antibody - NBP1-33043 from Novus Biologicals

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PPP2R2B Antibody [NBP1-33043] - Sample (30 ug of whole cell lysate) A: Hep G2 10% SDS PAGE; antibody diluted at 1:1000.

PPP2R2B Antibody - NBP1-92283 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PPP2R2B Antibody - H00005521-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: PPP2R2B Antibody [H00005521-D01P] - Analysis of PPP2R2B expression in mouse spleen.

PPP2R2B Antibody (2C11) - H00005521-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2C11

PPP2R2B Antibody (1F3) - H00005521-M02 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1F3
Immunoprecipitation: PPP2R2B Antibody (1F3) [H00005521-M02] - Analysis of PPP2R2B transfected lysate using anti-PPP2R2B monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with PPP2R2B MaxPab rabbit polyclonal antibody.

PPP2R2B Antibody (1B10) - H00005521-M23 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1B10
Immunoprecipitation: PPP2R2B Antibody (1B10) [H00005521-M23] - Analysis of PPP2R2B transfected lysate using anti-PPP2R2B monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with PPP2R2B rabbit polyclonal antibody.

PPP2R2B/PP2A-B55 Polyclonal Antibody - bs-11749R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PPP2R2B/PP2A-B55 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11749R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PPP2R2B/PP2A-B55 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11749R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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