| Gene Symbol |
NDUFB3
|
| Entrez Gene |
4709
|
| Alt Symbol |
B12, CI-B12
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
|
| Other Description |
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3|NADH-ubiquinone oxidoreductase B12 subunit|complex I-B12
|
| Swissprots |
Q6IB80 O43676
|
| Accessions |
AAX88972 EAW70233 EAW70234 O43676 AF035839 AAC15590 AF047183 AAC04268 BC018183 AAH18183 BM848639 BU188560 CR456924 CAG33205 DQ891431 ABM82357 DQ894606 ABM85532 XM_011511230 XP_011509532 NM_001257102 NP_001244031 NM_002491 NP_002482
|
| Function |
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
|
| Subcellular Location |
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
|
| Top Pathways |
Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation
|