Gene Symbol | NDUFB3 |
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Entrez Gene | 4709 |
Alt Symbol | B12, CI-B12 |
Species | Human |
Gene Type | protein-coding |
Description | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa |
Other Description | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3|NADH-ubiquinone oxidoreductase B12 subunit|complex I-B12 |
Swissprots | Q6IB80 O43676 |
Accessions | AAX88972 EAW70233 EAW70234 O43676 AF035839 AAC15590 AF047183 AAC04268 BC018183 AAH18183 BM848639 BU188560 CR456924 CAG33205 DQ891431 ABM82357 DQ894606 ABM85532 XM_011511230 XP_011509532 NM_001257102 NP_001244031 NM_002491 NP_002482 |
Function | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
Subcellular Location | Mitochondrion inner membrane; Single-pass membrane protein; Matrix side. |
Top Pathways | Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |
NDUFB3 CRISPR/Cas9 KO Plasmid (h) - sc-417178 from Santa Cruz Biotechnology
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NDUFB3 HDR Plasmid (h) - sc-417178-HDR from Santa Cruz Biotechnology
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NDUFB3 Double Nickase Plasmid (h) - sc-417178-NIC from Santa Cruz Biotechnology
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NDUFB3 Double Nickase Plasmid (h2) - sc-417178-NIC-2 from Santa Cruz Biotechnology
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NDUFB3 CRISPR Activation Plasmid (h) - sc-417178-ACT from Santa Cruz Biotechnology
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NDUFB3 CRISPR Activation Plasmid (h2) - sc-417178-ACT-2 from Santa Cruz Biotechnology
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NDUFB3 Lentiviral Activation Particles (h) - sc-417178-LAC from Santa Cruz Biotechnology
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NDUFB3 Lentiviral Activation Particles (h2) - sc-417178-LAC-2 from Santa Cruz Biotechnology
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NDUFB3 siRNA (h) - sc-94549 from Santa Cruz Biotechnology
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NDUFB3 shRNA Plasmid (h) - sc-94549-SH from Santa Cruz Biotechnology
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NDUFB3 shRNA (h) Lentiviral Particles - sc-94549-V from Santa Cruz Biotechnology
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NDUFB3 RNAi - H00004709-R01 from Novus Biologicals
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MISSION® esiRNA - EHU033111 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15157 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15157 from Sigma-Aldrich
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NDUFB3 siRNA (Human) - CRH3123 from Cohesion Biosciences
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shRNA set against Human NDUFB3 (NM_002491.2) - SHH350732 from Creative biogene
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shRNA set against Human NDUFB3(NM_002491.2) - SHR005214 from Creative biogene
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NDUFB3 shRNA Plasmid (Human) - CHH3123 from Cohesion Biosciences
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NDUFB3 miRNA 3'UTR clone - MiUTR1H-06704 from Creative biogene
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