Gene Symbol | ST18 |
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Entrez Gene | 9705 |
Alt Symbol | NZF3, ZC2HC10, ZNF387 |
Species | Human |
Gene Type | protein-coding |
Description | suppression of tumorigenicity 18, zinc finger |
Other Description | neural zinc finger transcription factor 3|suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein)|suppression of tumorigenicity 18 protein|zinc finger protein 387 |
Swissprots | O60284 Q17RY1 |
Accessions | EAW86715 EAW86716 EAW86717 O60284 AB011107 BAA25461 AK311188 BC025662 BC026316 BC031075 BC117147 AAI17148 BC117149 AAI17150 BC143871 BC143872 BC143873 BC143875 BQ639545 DA288225 XM_006716487 XP_006716550 XM_011517629 XP_011515931 XM_011517630 XP_011515932 XM_011517631 XP_011515933 XM_011517632 XP_011515934 XM_011517633 XP_011515935 XM_011517634 XP_011515936 XM_011517635 XP_011515937 XM_011517636 XP_011515938 XM_011517637 XP_011515939 XM_011517638 XP_011515940 XM_011517639 XP_011515941 XM_011517640 XP_011515942 XM_011517641 XP_011515943 XM_011517642 XP_011515944 NM_014682 NP_055497 |
Function | Repressor that binds to DNA sequences containing a bipartite element consisting of a direct repeat of the sequence 5'-AAAGTTT-3' separated by 2-9 nucleotides. Represses basal transcription activity from target promoters (By similarity). Inhibits colony formation in cultured breast cancer cells. {ECO:0000250, ECO:0000269|PubMed:15489893}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:15489893}. |
Tissue Specificity | Detected at low levels in heart, liver, kidney, skeletal muscle, pancreas, testis, ovary and prostate. Detected at even lower levels in mammary epithelial cells and breast cancer cells. {ECO:0000269|PubMed:15489893}. |
ST18 CRISPR/Cas9 KO Plasmid (h) - sc-407660 from Santa Cruz Biotechnology
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ST18 HDR Plasmid (h) - sc-407660-HDR from Santa Cruz Biotechnology
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ST18 Double Nickase Plasmid (h) - sc-407660-NIC from Santa Cruz Biotechnology
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ST18 Double Nickase Plasmid (h2) - sc-407660-NIC-2 from Santa Cruz Biotechnology
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ST18 CRISPR Activation Plasmid (h) - sc-407660-ACT from Santa Cruz Biotechnology
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ST18 CRISPR Activation Plasmid (h2) - sc-407660-ACT-2 from Santa Cruz Biotechnology
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ST18 Lentiviral Activation Particles (h) - sc-407660-LAC from Santa Cruz Biotechnology
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ST18 Lentiviral Activation Particles (h2) - sc-407660-LAC-2 from Santa Cruz Biotechnology
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ST18 siRNA (h) - sc-77586 from Santa Cruz Biotechnology
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ST18 shRNA Plasmid (h) - sc-77586-SH from Santa Cruz Biotechnology
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ST18 shRNA (h) Lentiviral Particles - sc-77586-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU122261 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20650 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20650 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00031 from Sigma-Aldrich
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ST18 siRNA (Human) - CRH6476 from Cohesion Biosciences
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ST18 RNAi - H00009705-R01 from Novus Biologicals
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ST18 - MBS8220516 from MyBioSource
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shRNA set against Human ST18 (NM_014682.2) - SHH418768 from Creative biogene
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Human ST18 siRNA - orb266978 from Biorbyt
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ST18 shRNA Plasmid (Human) - CHH6476 from Cohesion Biosciences
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