Atg16l1

Gene Symbol Atg16l1
Entrez Gene 77040
Alt Symbol 1500009K01Rik, Apg16l, Atg16l, WDR30
Species Mouse
Gene Type protein-coding
Description autophagy related 16-like 1 (S. cerevisiae)
Other Description APG16-like 1|Atg16L1 gamma|autophagy-related 16-like 1 gamma|autophagy-related protein 16-1
Swissprots Q80Y53 Q80U97 Q8C0J2 Q9DB63 Q80U99 Q80U98 Q6KAT7
Accessions EDL40144 EDL40145 EDL40146 EDL40147 EDL40148 Q8C0J2 AB087879 BAC55090 AB087880 BAC55091 AB087881 BAC55092 AB476646 BAL42358 AK005181 BAB23866 AK030983 BAC27201 AK048873 AK131120 BAD21370 AK134333 AK145673 AK155358 BAE33214 AK163246 BAE37254 AK170073 BAE41546 AK202676 AK218161 BC033362 BC049122 AAH49122 BC052087 BE988512 XM_006529950 XP_006530013 XR_387198 NM_001205391 NP_001192320 NM_001205392 NP_001192321 NM_029846 NP_084122
Function Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane. {ECO:0000269|PubMed:12665549, ECO:0000269|PubMed:24553140, ECO:0000269|PubMed:24954904}.
Subcellular Location Cytoplasm. Preautophagosomal structure membrane {ECO:0000269|PubMed:24954904}; Peripheral membrane protein {ECO:0000305}. Note=Recruited to omegasomes membranes by WIPI2. Omegasomes are endoplasmic reticulum connected strutures at the origin of preautophagosomal structures. Localized to preautophagosomal structure (PAS) where it is involved in the membrane targeting of ATG5. Localizes also to discrete punctae along the ciliary axoneme. {ECO:0000269|PubMed:24954904}.
Tissue Specificity Widely expressed. In the liver, isoform 2 is highly expressed and isoform 1 is weakly expressed. Isoform 3 is expressed in the brain. {ECO:0000269|PubMed:12665549}.
Top Pathways Regulation of autophagy

Anti-ATG16L1 antibody - ab64780 from Abcam

Host Sheep
Clonality Polyclonal

ATG16L1 Antibody - NB110-82384 from Novus Biologicals

Prices $99.00, $279.00
Sizes 25 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ATG16L1 Antibody [NB110-82384] - Analysis of ATG16L1 in HeLa whole cell extracts.

ATG16L1 Antibody - NBP1-20890 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: ATG16L1 Antibody [NBP1-20890] - (0.1ug/ml) staining of Mouse Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

ATG16L1 Antibody [HRP] - NB110-82384H from Novus Biologicals

Prices $319.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ATG16L1 Antibody [DyLight 488] - NB110-82384G from Novus Biologicals

Prices $319.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ATG16L1 Antibody [DyLight 550] - NB110-82384R from Novus Biologicals

Prices $319.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ATG16L1 Antibody [DyLight 650] - NB110-82384C from Novus Biologicals

Prices $319.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ATG16L1 Antibody [Biotin] - NB110-82384B from Novus Biologicals

Prices $299.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ATG16L1 Antibody [Alexa Fluor (R) 700] - NB110-82384AF700 from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Rabbit
Clonality Polyclonal

ATG16L1 Antibody [Alexa Fluor (R) 647] - NB110-82384AF647 from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Rabbit
Clonality Polyclonal

ATG16L1 Antibody [Alexa Fluor (R) 488] - NB110-82384AF488 from Novus Biologicals

Prices $329.00
Sizes 100 tests
Host Rabbit
Clonality Polyclonal

ATG16L1 Antibody [Alexa Fluor (R) 405] - NB110-82384AF405 from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Rabbit
Clonality Polyclonal

ATG16L1 Antibody [FITC] - NB110-82384F from Novus Biologicals

Prices $299.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ATG16L1 Antibody [DyLight 405] - NB110-82384V from Novus Biologicals

Prices $319.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ATG16L1 antibody, Internal - GTX88747 from GeneTex

Prices $319.00
Sizes 100 μg
Host Goat
Clonality Polyclonal
Anti-ATG16L1 antibody, Internal used in Western blot. GTX88747

ATG16L antibody - orb33383 from Biorbyt

Prices $187.00, $383.00
Sizes 80 μl (Trial size), 400 μl
Host Rabbit
Clonality Polyclonal

Atg16 Autophagy Related 16-Like 1 (S. Cerevisiae) Antibody - abx111108 from Abbexa

Host Rabbit
Clonality Polyclonal
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