Gene Symbol | ILF2 |
---|---|
Entrez Gene | 3608 |
Alt Symbol | NF45, PRO3063 |
Species | Human |
Gene Type | protein-coding |
Description | interleukin enhancer binding factor 2 |
Other Description | interleukin enhancer binding factor 2, 45kD|interleukin enhancer binding factor 2, 45kDa|interleukin enhancer-binding factor 2|nuclear factor of activated T-cells, 45-kDa |
Swissprots | Q9BWD4 Q9P1N0 Q12905 A6NDB0 Q5SR11 Q5SR10 B2R8G7 Q7L7R3 |
Accessions | AAM45141 CAI18796 EAW53285 EAW53286 Q12905 AK223326 BAD97046 AK302214 BAG63571 AK310615 AK313364 BAG36164 BC000382 AAH00382 BM800544 BX450311 DC412988 DQ891378 ABM82304 DQ894555 ABM85481 HQ322261 AEE02016 HQ322262 AEE02017 U10323 AAA20993 NM_001267809 NP_001254738 NM_004515 NP_004506 |
Function | Appears to function predominantly as a heterodimeric complex with ILF3. This complex may regulate transcription of the IL2 gene during T-cell activation. It can also promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA. Essential for the efficient reshuttling of ILF3 (isoform 1 and isoform 2) into the nucleus. {ECO:0000269|PubMed:10574923, ECO:0000269|PubMed:11739746, ECO:0000269|PubMed:21123651, ECO:0000269|PubMed:9442054}. |
Subcellular Location | Nucleus, nucleolus. Cytoplasm. Nucleus. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. |
NF45 CRISPR/Cas9 KO Plasmid (h) - sc-402042 from Santa Cruz Biotechnology
|
||||||||
NF45 HDR Plasmid (h) - sc-402042-HDR from Santa Cruz Biotechnology
|
||||||||
NF45 Double Nickase Plasmid (h) - sc-402042-NIC from Santa Cruz Biotechnology
|
||||||||
NF45 Double Nickase Plasmid (h2) - sc-402042-NIC-2 from Santa Cruz Biotechnology
|
||||||||
NF45 CRISPR Activation Plasmid (h) - sc-402042-ACT from Santa Cruz Biotechnology
|
||||||||
NF45 CRISPR Activation Plasmid (h2) - sc-402042-ACT-2 from Santa Cruz Biotechnology
|
||||||||
NF45 Lentiviral Activation Particles (h) - sc-402042-LAC from Santa Cruz Biotechnology
|
||||||||
NF45 Lentiviral Activation Particles (h2) - sc-402042-LAC-2 from Santa Cruz Biotechnology
|
||||||||
NF45 siRNA (h) - sc-62683 from Santa Cruz Biotechnology
|
||||||||
NF45 shRNA Plasmid (h) - sc-62683-SH from Santa Cruz Biotechnology
|
||||||||
NF45 shRNA (h) Lentiviral Particles - sc-62683-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU084311 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN10646 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10646 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR02713 from Sigma-Aldrich
|
||||||||
ILF2 siRNA (Human) - CRH2415 from Cohesion Biosciences
|
||||||||
ILF2 RNAi - H00003608-R01 from Novus Biologicals
|
||||||||
ILF2 - MBS827450 from MyBioSource
|
||||||||
shRNA set against Human ILF2 (NM_004515.3) - SHH319173 from Creative biogene
|
||||||||
Human ILF2 siRNA - orb262917 from Biorbyt
|
||||||||
ILF2 shRNA Plasmid (Human) - CHH2415 from Cohesion Biosciences
|
||||||||
ILF2 miRNA 3'UTR clone - MiUTR3H-05745 from Creative biogene
|