Gene Symbol |
AMBP
|
Entrez Gene |
259
|
Alt Symbol |
A1M, EDC1, HCP, HI30, IATIL, ITI, ITIL, ITILC, UTI
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
alpha-1-microglobulin/bikunin precursor
|
Other Description |
bikunin|complex-forming glycoprotein heterogeneous in charge|growth-inhibiting protein 19|inter-alpha-trypsin inhibitor light chain|protein AMBP|protein HC|trypstatin|uristatin|uronic-acid-rich protein
|
Swissprots |
P00977 Q9UDI8 Q9UC58 P78491 Q5TBD7 Q2TU33 P02759 P02760
|
Accessions |
AAA59196 CAA37726 CAA38585 CAA38586 CAA38587 CAJ44933 CBF57586 EAW87404 P02760 AK290837 BAF83526 AK303795 BAH14052 AK310776 AK310791 AY544123 AAT11154 BC041593 AAH41593 CB141734 HQ448440 ADQ32920 M11562 AAA59194 X04225 CAA27803 X04494 CAA28182 NM_001633 NP_001624
|
Function |
Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization. {ECO:0000269|PubMed:7676539}.
|
Subcellular Location |
Secreted.
|
Tissue Specificity |
Expressed by the liver and secreted in plasma. Alpha-1-microglobulin occurs in many physiological fluids including plasma, urine, and cerebrospinal fluid. Inter-alpha- trypsin inhibitor is present in plasma and urine.
|