Gene Symbol | GSTP1 |
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Entrez Gene | 2950 |
Alt Symbol | DFN7, FAEES3, GST3, GSTP, HEL-S-22, PI |
Species | Human |
Gene Type | protein-coding |
Description | glutathione S-transferase pi 1 |
Other Description | GST class-pi|GSTP1-1|deafness, X-linked 7|epididymis secretory protein Li 22|fatty acid ethyl ester synthase III|glutathione S-transferase P |
Swissprots | P09211 Q5TZY3 Q15690 O00460 |
Accessions | AAA56823 AAA64919 AAC13869 AAP72967 ACB45879 CAA30847 CAA30894 EAW74648 EAW74649 EAW74650 P09211 AY579414 BC010915 AAH10915 BC044846 BT019949 AAV38752 BT019950 AAV38753 CA946272 CR450361 CAG29357 D28456 BAA05822 DQ892738 ABM83664 DQ895985 ABM86911 EU794620 ACJ13674 GQ141553 ACT66687 GQ141554 ACT66688 M69113 U30897 AAC51280 U62589 AAC51237 X06547 CAA29794 X15480 CAA33508 NM_000852 NP_000843 |
Function | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration. {ECO:0000269|PubMed:21668448}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:19269317}. Mitochondrion {ECO:0000269|PubMed:19269317}. Nucleus {ECO:0000269|PubMed:19269317}. Note=The 83 N-terminal amino acids function as un uncleaved transit peptide, and arginine residues within it are crucial for mitochondrial localization. |
Top Pathways | Prostate cancer, Chemical carcinogenesis, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450, Drug metabolism - cytochrome P450 |
Active human Glutathione S Transferase pi full length protein - ab167990 from Abcam
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GST3 / GST pi peptide (21-32) - ab45747 from Abcam
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Human GST3 / GST pi full length protein - ab86703 from Abcam
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GSTP1 / GST Pi Antibody Blocking Peptide - LS-E7213 from LifeSpan Bioscience
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GSTP1 / GST Pi Antibody Blocking Peptide - LS-E25894 from LifeSpan Bioscience
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GSTP1 / GST Pi Antibody Blocking Peptide - LS-E30426 from LifeSpan Bioscience
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GSTP1 / GST Pi Antibody Blocking Peptide - LS-E17542 from LifeSpan Bioscience
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Recombinant Human Glutathione S-Transferase pi 1/GSTP1 Protein - NBC1-28777 from Novus Biologicals
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Glutathione S-Transferase pi 1/GSTP1 Recombinant Protein - H00002950-P01 from Novus Biologicals
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Recombinant Human Glutathione S-Transferase pi 1/GSTP1 Protein - NBC1-28778 from Novus Biologicals
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Glutathione S-Transferase pi 1/GSTP1 Recombinant Protein - P3490 from Novus Biologicals
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Glutathione S-Transferase pi 1/GSTP1 Blocking Peptide - NBP1-76857PEP from Novus Biologicals
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GSTP1-Antibody-C-term-Blocking-Peptide - BP2932b from Abgent, a WuXi AppTec company
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GSTP1 blocking peptide - GTX89536-PEP from GeneTex
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Recombinant Human GSTP1, CF - 6455-GT-010 from R&D Systems
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Recombinant rat Glutathione S-transferase P (OPCA00107) - OPCA00107 from Aviva Systems Biology
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Recombinant human Glutathione S-transferase P (OPCA00865) - OPCA00865 from Aviva Systems Biology
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Recombinant human Glutathione S-transferase P (OPCA00866) - OPCA00866 from Aviva Systems Biology
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GSTP1 Protein (OPPA01919) - OPPA01919 from Aviva Systems Biology
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Human FAEES3 protein - orb246686 from Biorbyt
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Human GSTP1 protein - orb90135 from Biorbyt
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GSTP1-1 protein - orb197651 from Biorbyt
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GSTP1 Blocking Peptide - 33R-9350 from Fitzgerald
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GSTP1 Blocking Peptide - 33R-10640 from Fitzgerald
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GSTP1 protein - 30R-3251 from Fitzgerald
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