GSTP1

Gene Symbol GSTP1
Entrez Gene 2950
Alt Symbol DFN7, FAEES3, GST3, GSTP, HEL-S-22, PI
Species Human
Gene Type protein-coding
Description glutathione S-transferase pi 1
Other Description GST class-pi|GSTP1-1|deafness, X-linked 7|epididymis secretory protein Li 22|fatty acid ethyl ester synthase III|glutathione S-transferase P
Swissprots P09211 Q5TZY3 Q15690 O00460
Accessions AAA56823 AAA64919 AAC13869 AAP72967 ACB45879 CAA30847 CAA30894 EAW74648 EAW74649 EAW74650 P09211 AY579414 BC010915 AAH10915 BC044846 BT019949 AAV38752 BT019950 AAV38753 CA946272 CR450361 CAG29357 D28456 BAA05822 DQ892738 ABM83664 DQ895985 ABM86911 EU794620 ACJ13674 GQ141553 ACT66687 GQ141554 ACT66688 M69113 U30897 AAC51280 U62589 AAC51237 X06547 CAA29794 X15480 CAA33508 NM_000852 NP_000843
Function Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration. {ECO:0000269|PubMed:21668448}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:19269317}. Mitochondrion {ECO:0000269|PubMed:19269317}. Nucleus {ECO:0000269|PubMed:19269317}. Note=The 83 N-terminal amino acids function as un uncleaved transit peptide, and arginine residues within it are crucial for mitochondrial localization.
Top Pathways Prostate cancer, Chemical carcinogenesis, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450, Drug metabolism - cytochrome P450

GSTP1 (3F2) Mouse mAb - 3369 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Mouse
Clonality Monoclonal
Clone 3F2
Western blot analysis of extracts from PC3 cells and human cerebellum using GSTP1 (3F2) Mouse mAb.

GSTP1 (F-6) - sc-376481 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
GSTP1/2 (F-6): sc-376481. Western blot analysis of GSTP1/2 expression in PC-3 (A) and K-562 (B) whole cell lysates.

GSTP1 (H-11) - sc-376013 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
GSTP1/2 (H-11): sc-376013. Western blot analysis of GSTP1/2 expression in PC-3 (A) and K-562 (B) whole cell lysates.

GSTP1 (N-18) - sc-28494 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
GSTP1 (N-18): sc-28494. Western blot analysis of GSTP1 expression in K-562 (A), NCI-H1688 (B), PC-3 (C), JAR (D) and JEG-3 (E) whole cell lysates.

GSTP1 (FL-210) - sc-134469 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
GSTP1/2 (FL-210): sc-134469. Western blot analysis of GSTP1/2 expression in PC-3 (A), K-562 (B) and 293T (C) whole cell lysates.

GSTP1 (3F2C2) - sc-66000 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
GSTP1 (3F2C2): sc-66000. Western blot analysis of GSTP1 expression in NCI-H1688 (A) and PC-3 (B) whole cell lysates and human prostate tissue extract (C).

Anti-Glutathione S Transferase pi antibody - C-terminal - ab135535 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Glutathione S Transferase pi antibody - C-terminal (ab135535) at 1/50 dilution + Y79 cell line lysate at 35 µg

Anti-GST3 / GST pi antibody - ab53943 from Abcam

Prices $394.00
Sizes 50 µl
Host Goat
Clonality Polyclonal
IHC image of ab53943 staining in human normal liver formalin fixed paraffin embedded tissue section, performed on a Leica BondTM system using the standard protocol B. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab53943, 5µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-GST3 / GST pi antibody - ab153949 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescent analysis methanol fixed HeLa cells; labeling GST3 / GST pi with ab153949 at 1/200 dilution. Blue: Hoechst 33343 staining

Anti-GST3 / GST pi antibody - ab117885 from Abcam

Prices $384.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-GST3 / GST pi antibody (ab117885) at 1 µg/mlLane 1 : Prostate (Human) Whole Cell Lysate - liver cirrhosis (ab30307)Lane 2 : PC3 (Human prostate carcinoma cell line) Whole Cell LysateLane 3 : HeLa (Human epithelial carcinoma cell line) Whole Cell LysateLane 4 : HEK293 (Human embryonic kidney cell line) Whole Cell Lysate Lane 5 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell LysateLane 6 : K562 (Human erythromyeloblastoid leukemia cell line) Whole Cell LysateLane 7 : Kidney (Human) Tissue Lysate - adult normal tissue (ab30203)Lysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-GST3 / GST pi antibody - ab106268 from Abcam

Prices $384.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-GST3 / GST pi antibody (ab106268) at 2 µg/ml + HeLa cell lysate

Anti-GST3 / GST pi antibody - ab124503 from Abcam

Prices $384.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-GST3 / GST pi antibody (ab124503) at 0.5 µg/mlLane 2 : Anti-GST3 / GST pi antibody (ab124503) at 1 µg/mlLane 1 : Jurkat cell lysateLane 2 : Jurkat cell lysateLysates/proteins at 15 µg per lane.

Anti-GST3 / GST pi antibody - ab129456 from Abcam

Prices $384.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human ovarian carcinoma tissue labelling GST3 / GST pi with ab129456 at 1/5000 (0.2µg/ml). Detection: DAB.

Anti-GST3 / GST pi antibody - ab97515 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-GST3 / GST pi antibody (ab97515) at 1/5000 dilution + A431 whole cell lysate at 30 µg

Anti-GST3 / GST pi antibody [3F2C2] - ab47709 from Abcam

Prices $401.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3F2C2
Immunohistochemical analysis of paraffin-embedded normal human prostate tissue, showing cytoplasmic/ nuclear localization , using ab47709 at a 1/500 dilution, with DAB staining.

Anti-GST3 / GST pi antibody [EPR8262] - ab134934 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR8262
All lanes : Anti-GST3 / GST pi antibody [EPR8262] (ab134934) at 1/1000 dilutionLane 1 : K562 cell lysateLane 2 : Jurkat cell lysateLysates/proteins at 10 µg per lane.SecondaryStandard HRP labelled goat anti-rabbit at 1/2000 dilution

Anti-GST3 / GST pi antibody [EPR8263] - ab138491 from Abcam

Prices $387.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR8263
All lanes : Anti-GST3 / GST pi antibody [EPR8263] (ab138491) at 1/1000 dilutionLane 1 : K562 lysateLane 2 : PC3 lysateLane 3 : Human cerebellum lysateLane 4 : Jurkat lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-GST3 / GST pi antibody, prediluted - ab74163 from Abcam

Prices $376.00
Sizes 7 ml
Host Rabbit
Clonality Polyclonal
Human liver stained with ab74163 by Immnohistochemistry Formailin-fixed, Paraffin-embedded tissue using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of epithelial cells in bile ducts.

Anti-GSTP1 / GST Pi Antibody - LS-C23911 from LifeSpan Bioscience

Host Sheep
Clonality Polyclonal

Anti-GSTP1 / GST Pi Antibody - LS-C23908 from LifeSpan Bioscience

Prices $515.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-GSTP1 / GST Pi Antibody - LS-C23910 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-GSTP1 / GST Pi Antibody - LS-C23909 from LifeSpan Bioscience

Prices $345.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-GSTP1 / GST Pi Antibody (aa1-211) - LS-C36488 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-GSTP1 / GST Pi Antibody - LS-C36493 from LifeSpan Bioscience

Prices $315.00
Sizes 10 µg
Host Mouse
Clonality Monoclonal

Anti-GSTP1 / GST Pi Antibody - LS-C66736 from LifeSpan Bioscience

Prices $530.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
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