| Gene Symbol |
DNASE1L3
|
| Entrez Gene |
1776
|
| Alt Symbol |
DHP2, DNAS1L3, LSD, SLEB16
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
deoxyribonuclease I-like 3
|
| Other Description |
DNase I homolog protein 2|DNase I homolog protein DHP2|DNase I-like 3|DNase gamma|LS-DNase|Liver and spleen DNase|deoxyribonuclease I-like III|deoxyribonuclease gamma
|
| Swissprots |
B2R8B1 Q13609 O75803 B7Z707
|
| Accessions |
EAW65358 EAW65359 Q13609 AB209613 BAD92850 AF047354 AAC35752 AI591302 AI660448 AK131323 BAG54766 AK301263 BAH13443 AK313303 BAG36108 BC015831 AAH15831 BI521582 BI834035 DB164811 DQ892850 ABM83776 DQ896097 ABM87096 U56814 AAB63967 NM_001256560 NP_001243489 NM_004944 NP_004935
|
| Function |
Has DNA hydrolytic activity. Does not bind to actin. Cleaves chromatin DNA to nucleosomal units.
|
| Subcellular Location |
Nucleus. Note=May first pass through the ER membrane before being imported in the nucleus.
|
| Tissue Specificity |
Liver and spleen.
|
![Western Blot: DNASE1L3 Overexpression Lysate (Adult Normal) [NBL1-09963] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for DNASE1L3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/3852_DNASE1L3%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-09963-img0002.jpg)