Gene Symbol | DNASE1L3 |
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Entrez Gene | 1776 |
Alt Symbol | DHP2, DNAS1L3, LSD, SLEB16 |
Species | Human |
Gene Type | protein-coding |
Description | deoxyribonuclease I-like 3 |
Other Description | DNase I homolog protein 2|DNase I homolog protein DHP2|DNase I-like 3|DNase gamma|LS-DNase|Liver and spleen DNase|deoxyribonuclease I-like III|deoxyribonuclease gamma |
Swissprots | B2R8B1 Q13609 O75803 B7Z707 |
Accessions | EAW65358 EAW65359 Q13609 AB209613 BAD92850 AF047354 AAC35752 AI591302 AI660448 AK131323 BAG54766 AK301263 BAH13443 AK313303 BAG36108 BC015831 AAH15831 BI521582 BI834035 DB164811 DQ892850 ABM83776 DQ896097 ABM87096 U56814 AAB63967 NM_001256560 NP_001243489 NM_004944 NP_004935 |
Function | Has DNA hydrolytic activity. Does not bind to actin. Cleaves chromatin DNA to nucleosomal units. |
Subcellular Location | Nucleus. Note=May first pass through the ER membrane before being imported in the nucleus. |
Tissue Specificity | Liver and spleen. |
DNASE1L3 CRISPR/Cas9 KO Plasmid (h) - sc-418477 from Santa Cruz Biotechnology
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DNASE1L3 HDR Plasmid (h) - sc-418477-HDR from Santa Cruz Biotechnology
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DNASE1L3 Double Nickase Plasmid (h) - sc-418477-NIC from Santa Cruz Biotechnology
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DNASE1L3 Double Nickase Plasmid (h2) - sc-418477-NIC-2 from Santa Cruz Biotechnology
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DNASE1L3 CRISPR Activation Plasmid (h) - sc-418477-ACT from Santa Cruz Biotechnology
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DNASE1L3 CRISPR Activation Plasmid (h2) - sc-418477-ACT-2 from Santa Cruz Biotechnology
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DNASE1L3 Lentiviral Activation Particles (h) - sc-418477-LAC from Santa Cruz Biotechnology
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DNASE1L3 Lentiviral Activation Particles (h2) - sc-418477-LAC-2 from Santa Cruz Biotechnology
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DNASE1L3 siRNA (h) - sc-77163 from Santa Cruz Biotechnology
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DNASE1L3 shRNA Plasmid (h) - sc-77163-SH from Santa Cruz Biotechnology
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DNASE1L3 shRNA (h) Lentiviral Particles - sc-77163-V from Santa Cruz Biotechnology
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DNASE1L3 RNAi - H00001776-R01 from Novus Biologicals
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MISSION® esiRNA - EHU022441 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7391 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7391 from Sigma-Aldrich
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DNASE1L3 siRNA (Human) - CRH1234 from Cohesion Biosciences
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DNASE1L3 - MBS828149 from MyBioSource
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shRNA set against Human DNASE1L3 (NM_004944.3) - SHH279821 from Creative biogene
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DNASE1L3 shRNA Plasmid (Human) - CHH1234 from Cohesion Biosciences
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DNASE1L3 miRNA 3'UTR clone - MiUTR3H-04814 from Creative biogene
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