MED24

Gene Symbol MED24
Entrez Gene 9862
Alt Symbol ARC100, CRSP100, CRSP4, DRIP100, THRAP4, TRAP100
Species Human
Gene Type protein-coding
Description mediator complex subunit 24
Other Description CRSP complex subunit 4|activator-recruited cofactor 100 kDa component|cofactor required for Sp1 transcriptional activation subunit 4|cofactor required for Sp1 transcriptional activation, subunit 4, 100kDa|mediator of RNA polymerase II transcription subunit 24|mediator of RNA polymerase II transcription, subunit 24 homolog|thyroid hormone receptor associated protein 4|thyroid hormone receptor-associated protein 4|thyroid hormone receptor-associated protein complex 100 kDa component|vitamin D3 receptor-interacting protein complex 100 kDa component|vitamin D3 receptor-interacting protein complex component DRIP100
Swissprots A8K4S5 Q9NNY5 Q14143 B3KMR9 O75448
Accessions CAH05649 EAW60629 EAW60630 EAW60631 O75448 AF055995 AAC39855 AF277379 AAF78764 AK022508 BAG51081 AK291040 BAF83729 AK293309 BAG56829 AK299864 BAG61718 AK300992 BAG62611 AK303502 BAG64535 AK303745 BAG64717 BC011375 AAH11375 D50920 BAA09479 DB144359 DQ891082 ABM82008 DQ894264 ABM85190 EU392533 ACB88915 EU392534 ACB88916 EU392535 ACB88917 EU392536 ACB88918 EU392537 ACB88919 EU392538 ACB88920 EU392539 ACB88921 EU392540 ACB88922 EU392541 ACB88923 EU392542 ACB88924 EU392543 ACB88925 EU392544 ACB88926 EU392545 ACB88927 EU392546 ACB88928 EU392547 ACB88929 EU392548 EU392549 EU392550 EU392551 EU392552 EU392553 EU392554 XM_005257874 XP_005257931 XM_006722204 XP_006722267 XM_006722206 XP_006722269 XM_006722207 XP_006722270 XM_011525529 XP_011523831 XM_011525530 XP_011523832 XM_011525531 XP_011523833 XM_011525532 XP_011523834 XM_011525533 XP_011523835 XM_011525534 XP_011523836 XM_011525535 XP_011523837 XM_011525536 XP_011523838 XM_011525537 XP_011523839 XM_011525538 XP_011523840 XR_934627 NM_001079518 NP_001072986 NM_001267797 NP_001254726 NM_014815 NP_055630 NR_052017
Function Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. {ECO:0000269|PubMed:12218053, ECO:0000269|PubMed:16595664}.
Subcellular Location Nucleus {ECO:0000305}.
Tissue Specificity Ubiquitous. Abundant in skeletal muscle, heart and placenta. {ECO:0000269|PubMed:9653119}.

TRAP100 CRISPR/Cas9 KO Plasmid (h) - sc-417318 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRAP100 HDR Plasmid (h) - sc-417318-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRAP100 Double Nickase Plasmid (h) - sc-417318-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRAP100 Double Nickase Plasmid (h2) - sc-417318-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRAP100 CRISPR Activation Plasmid (h) - sc-417318-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRAP100 CRISPR Activation Plasmid (h2) - sc-417318-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRAP100 Lentiviral Activation Particles (h) - sc-417318-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRAP100 Lentiviral Activation Particles (h2) - sc-417318-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRAP100 siRNA (h) - sc-38589 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TRAP100 shRNA Plasmid (h) - sc-38589-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TRAP100 shRNA (h) Lentiviral Particles - sc-38589-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU069201 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN13173 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13173 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03178 from Sigma-Aldrich

Category miRNA

MED24 siRNA (Human) - CRH6612 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human MED24 (NM_014815.3) - SHH340023 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human THRAP4(NM_001079518.1) - SHH223098 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human THRAP4(NM_014815.3) - SHH223116 from Creative biogene

Category siRNA
Species Reactivities Human

Human MED24 siRNA - orb267114 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MED24 shRNA Plasmid (Human) - CHH6612 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MED24 miRNA 3'UTR clone - MiUTR1H-10390 from Creative biogene

Species Reactivities Human

MED24 miRNA 3'UTR clone - MiUTR1H-10391 from Creative biogene

Species Reactivities Human
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