Gene Symbol | LYPD3 |
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Entrez Gene | 27076 |
Alt Symbol | C4.4A |
Species | Human |
Gene Type | protein-coding |
Description | LY6/PLAUR domain containing 3 |
Other Description | 2310061G07Rik|GPI-anchored metastasis-associated protein C4.4A homolog|GPI-anchored metastasis-associated protein homolog|MIG-C4|ly6/PLAUR domain-containing protein 3|matrigel-induced gene C4 protein |
Swissprots | Q9UJ74 O95274 |
Accessions | AAG09062 EAW57190 O95274 AF082889 AAD13751 AJ223603 CAA11469 AK075464 BAG52146 AK290905 BAF83594 AK314773 BAG37310 AL832153 CAI46120 AY359006 AAQ89365 BC039167 AAH39167 BC041061 BP367221 DA837818 HQ447474 ADQ31960 NM_014400 NP_055215 |
Function | Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression. {ECO:0000269|PubMed:11179665, ECO:0000269|PubMed:11245483, ECO:0000269|PubMed:12592373, ECO:0000269|PubMed:15012588}. |
Subcellular Location | Cell membrane; Lipid-anchor, GPI-anchor. |
Tissue Specificity | Expressed in placenta, skin and urothelium. Found in suprabasal keratinocytes of chronic wounds. Weak expression is found in esophagus and peripheral blood mononuclear cells. Found in the majority of primary and metastatic transitional cell carcinomas (TCCs) and as well in breast cancer tissues, but not in adjacent normal tissues. High expression is found in the tumor component of some noninvasive superficial lesions and in invasive and metastatic urothelial cancers. {ECO:0000269|PubMed:11179665, ECO:0000269|PubMed:12592373, ECO:0000269|PubMed:15012588}. |
Human LYPD3 full length protein - ab162072 from Abcam
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Human LYPD3 protein fragment - ab151813 from Abcam
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C4.4A / LYPD3 Antibody Blocking Peptide - LS-E29524 from LifeSpan Bioscience
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C4.4A / LYPD3 Antibody Blocking Peptide - LS-E29525 from LifeSpan Bioscience
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C4.4A / LYPD3 Antibody Blocking Peptide - LS-E23896 from LifeSpan Bioscience
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C4.4A / LYPD3 Antibody Blocking Peptide - LS-E23897 from LifeSpan Bioscience
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C4.4A / LYPD3 Antibody Blocking Peptide - LS-E29791 from LifeSpan Bioscience
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C4.4A / LYPD3 Antibody Blocking Peptide - LS-E29790 from LifeSpan Bioscience
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C4.4A/LYPD3 Recombinant Protein - H00027076-P01 from Novus Biologicals
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Recombinant Human C4.4A/LYPD3, CF - 5428-C4-050 from R&D Systems
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Human LYPD3 protein - orb49522 from Biorbyt
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LYPD3 - H00027076-P01-10 from Acris Antibodies
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LYPD3 - H00027076-P01-25 from Acris Antibodies
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Ly6, PLAUR Domain-Containing Protein 3, LYPD3, Human, Recombinant - 19-C487 from ARP American Research Products
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LYPD3 Recombinant Protein - 96-528 from ProSci
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Recombinant Human LYPD3 Protein - BP001610-C487 from Syd Labs
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Recombinant Human LYPD3, His tagged - LYPD3-3789H from Creative Biomart
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Recombinant Human LYPD3, His-tagged - LYPD3-1074H from Creative Biomart
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LYPD3 - PN201308 from Elabscience
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Human C4.4A / LYPD3 Protein (His Tag) - 11836-H08H-50 from Sino Biological
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Human LYPD3 / C4.4A Protein - LY3-H52H5 from ACROBiosystems
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Recombinant Human Ly6/PLAUR domain-containing protein 3(LYPD3) - CSB-YP013263HU CSB-EP013263HU CSB-BP013263HU CSB-MP013263HU from Cusabio
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Recombinant Human C4.4A/LYPD3 Protein, CF - 5428-C4 from R&D Systems
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Recombinant Human C4.4A / LYPD3 Protein (His tag) - PKSH030987 from Elabscience
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Human LYPD3 His tag protein - orb84138 from Biorbyt
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