| Gene Symbol |
PPAPDC1B
|
| Entrez Gene |
84513
|
| Alt Symbol |
DPPL1, HTPAP
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
phosphatidic acid phosphatase type 2 domain containing 1B
|
| Other Description |
diacylglycerol pyrophosphate like 1|phosphatidate phosphatase PPAPDC1B|phosphatidic acid phosphatase type 2 domain-containing protein 1B
|
| Swissprots |
C9JKF5 Q8NEB5 Q9BY45 Q3KQX6
|
| Accessions |
EAW63325 EAW63326 EAW63327 EAW63328 EAW63329 Q8NEB5 AA761242 AF212238 AAK14924 AK292118 BAF84807 BC033025 AAH33025 BC106014 AAI06015 BE856962 BQ272061 DB458595 HQ447359 ADQ31845 XM_005273661 XP_005273718 XM_005273663 XP_005273720 XM_011544670 XP_011542972 XM_011544671 XP_011542973 XM_011544672 XP_011542974 XM_011544673 XP_011542975 XM_011544674 XP_011542976 XM_011544675 XP_011542977 XR_949491 XR_949492 XR_949493 NM_001102559 NP_001096029 NM_001102560 NP_001096030 NM_032483 NP_115872
|
| Function |
Displays magnesium-independent phosphatidate phosphatase activity in vitro. Catalyzes the conversion of phosphatidic acid to diacylglycerol. May be a metastatic suppressor for hepatocellular carcinoma. {ECO:0000269|PubMed:16261160, ECO:0000269|PubMed:17590538}.
|
| Subcellular Location |
Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Ubiquitous. {ECO:0000269|PubMed:17590538}.
|
![Western Blot: PPAPDC1B/DPPL1 Overexpression Lysate (Adult Normal) [NBL1-14628] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for PPAPDC1B/DPPL1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1451_PPAPDC1B-DPPL1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-14628-img0002.jpg)