Gene Symbol |
ROR2
|
Entrez Gene |
4920
|
Alt Symbol |
BDB, BDB1, NTRKR2
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
receptor tyrosine kinase-like orphan receptor 2
|
Other Description |
neurotrophic tyrosine kinase receptor-related 2|tyrosine-protein kinase transmembrane receptor ROR2
|
Swissprots |
Q9HAY7 Q01974 Q5SPI5 Q9HB61 Q59GF5
|
Accessions |
EAW62798 EAW62799 EAW62800 EAW62801 EAW62802 Q01974 AA463746 AA626834 AB209154 BAD92391 BC033697 BC051273 BC126454 BC130522 AAI30523 BI089313 BQ446244 M97639 AAA60276 XM_005252008 XP_005252065 XM_005252009 XP_005252066 XM_006717121 XP_006717184 XM_011518721 XP_011517023 NM_004560 NP_004551
|
Function |
Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development. Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation. {ECO:0000269|PubMed:17717073}.
|
Subcellular Location |
Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
|