Gene Symbol | ROR2 |
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Entrez Gene | 4920 |
Alt Symbol | BDB, BDB1, NTRKR2 |
Species | Human |
Gene Type | protein-coding |
Description | receptor tyrosine kinase-like orphan receptor 2 |
Other Description | neurotrophic tyrosine kinase receptor-related 2|tyrosine-protein kinase transmembrane receptor ROR2 |
Swissprots | Q9HAY7 Q01974 Q5SPI5 Q9HB61 Q59GF5 |
Accessions | EAW62798 EAW62799 EAW62800 EAW62801 EAW62802 Q01974 AA463746 AA626834 AB209154 BAD92391 BC033697 BC051273 BC126454 BC130522 AAI30523 BI089313 BQ446244 M97639 AAA60276 XM_005252008 XP_005252065 XM_005252009 XP_005252066 XM_006717121 XP_006717184 XM_011518721 XP_011517023 NM_004560 NP_004551 |
Function | Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development. Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation. {ECO:0000269|PubMed:17717073}. |
Subcellular Location | Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. |
ROR2 CRISPR/Cas9 KO Plasmid (h) - sc-401324 from Santa Cruz Biotechnology
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ROR2 HDR Plasmid (h) - sc-401324-HDR from Santa Cruz Biotechnology
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ROR2 Double Nickase Plasmid (h) - sc-401324-NIC from Santa Cruz Biotechnology
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ROR2 Double Nickase Plasmid (h2) - sc-401324-NIC-2 from Santa Cruz Biotechnology
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ROR2 CRISPR Activation Plasmid (h) - sc-401324-ACT from Santa Cruz Biotechnology
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ROR2 CRISPR Activation Plasmid (h2) - sc-401324-ACT-2 from Santa Cruz Biotechnology
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ROR2 Lentiviral Activation Particles (h) - sc-401324-LAC from Santa Cruz Biotechnology
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ROR2 Lentiviral Activation Particles (h2) - sc-401324-LAC-2 from Santa Cruz Biotechnology
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ROR2 siRNA (h) - sc-72390 from Santa Cruz Biotechnology
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ROR2 shRNA Plasmid (h) - sc-72390-SH from Santa Cruz Biotechnology
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ROR2 shRNA (h) Lentiviral Particles - sc-72390-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU142811 from Sigma-Aldrich
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MISSION® siRNA - SIHK1993 from Sigma-Aldrich
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MISSION® siRNA - SIHK1994 from Sigma-Aldrich
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MISSION® siRNA - SIHK1992 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2230 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2230 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08134 from Sigma-Aldrich
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ROR2 siRNA (Human) - CRH3270 from Cohesion Biosciences
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ROR2 - MBS829946 from MyBioSource
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ROR2 CRISPR/Cas9 KO Plasmid (h2) - sc-401324-KO-2 from Santa Cruz Biotechnology
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ROR2 HDR Plasmid (h2) - sc-401324-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human Ror2 (NM_004560.3) - SHH397737 from Creative biogene
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Human ROR2 siRNA - orb263772 from Biorbyt
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ROR2 shRNA Plasmid (Human) - CHH3270 from Cohesion Biosciences
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