| Gene Symbol |
KIF18A
|
| Entrez Gene |
81930
|
| Alt Symbol |
MS-KIF18A, PPP1R99
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
kinesin family member 18A
|
| Other Description |
kinesin-like protein KIF18A|protein phosphatase 1, regulatory subunit 99
|
| Swissprots |
Q4VPE3 Q9H0F3 Q86VS5 Q8NI77
|
| Accessions |
EAW68271 Q8NI77 AB062483 BAB93508 AK093850 AK312576 BAG35470 AL136819 CAB66753 AM393105 CAL37983 AW770226 AY791349 AAX16185 BC026090 AAH26090 BC035917 BC048347 AAH48347 DB080843 NM_031217 NP_112494
|
| Function |
Microtubule-depolymerizing kinesin which plays a role in chromosome congression by reducing the amplitude of preanaphase oscillations and slowing poleward movement during anaphase, thus suppressing chromosome movements. May stabilize the CENPE-BUB1B complex at the kinetochores during early mitosis and maintains CENPE levels at kinetochores during chromosome congression. {ECO:0000269|PubMed:17346968, ECO:0000269|PubMed:18267093, ECO:0000269|PubMed:18513970, ECO:0000269|PubMed:19625775}.
|
| Subcellular Location |
Cell projection, ruffle. Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
|