| Gene Symbol |
TMEM8B
|
| Entrez Gene |
51754
|
| Alt Symbol |
C9orf127, NAG-5, NGX6
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
transmembrane protein 8B
|
| Other Description |
Protein NGX6|nasopharyngeal carcinoma expressed 6|nasopharyngeal carcinoma related protein|nasopharyngeal carcinoma-associated gene 6 protein|protein NAG-5
|
| Swissprots |
Q49AB1 Q4KMX5 Q9HBY2 A6NDV4 O75539 Q9P0U7 Q5TCW5 B3KQF3
|
| Accessions |
A6NDV4 CAF86955 EAW58325 EAW58326 EAW58327 EAW58328 AF070572 AAC28644 AF188239 AAG29055 AK074844 BAG52015 BC041377 BC043384 BC064951 BC082765 BC098265 AAH98265 BC098296 AAH98296 BC099733 AAH99733 XM_005251483 XP_005251540 XM_011517901 XP_011516203 XM_011517902 XP_011516204 XM_011517903 XP_011516205 XM_011517904 XP_011516206 XM_011517905 XP_011516207 XM_011517906 XP_011516208 XM_011517907 XP_011516209 XM_011517908 XP_011516210 XM_011517909 XP_011516211 XM_011517910 XP_011516212 XM_011517911 XP_011516213 XM_011517912 XP_011516214 XM_011517913 XP_011516215 XM_011517914 XP_011516216 XM_011517915 XP_011516217 XM_011517916 XP_011516218 XM_011517917 XP_011516219 XM_011517918 XP_011516220 XM_011517919 XP_011516221 NM_001042589 NP_001036054 NM_001042590 NP_001036055 NM_016446 NP_057530
|
| Function |
May function as a regulator of the EGFR pathway. Probable tumor suppressor which may function in cell growth, proliferation and adhesion. {ECO:0000269|PubMed:15498789, ECO:0000269|PubMed:15723283, ECO:0000269|PubMed:17270023, ECO:0000269|PubMed:17641538}.
|
| Subcellular Location |
Isoform 2: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Cytoplasm {ECO:0000305}. Nucleus {ECO:0000305}. Mitochondrion. Endoplasmic reticulum. Note=Also detected in mitochondrion and endoplasmic reticulum.
|