IRS1

Gene Symbol	IRS1
Entrez Gene	3667
Alt Symbol	HIRS-1
Species	Human
Gene Type	protein-coding
Description	insulin receptor substrate 1
Other Description	IRS-1
Swissprots	P35568
Accessions	AAB21608 AGG19175 AGG19176 AGG19177 AHG12642 AHG12643 AHG12644 CAD79961 CBL64020 EAW70838 EAW70839 P35568 AW469017 BC053895 AAH53895 EU831611 ACE87211 EU831698 ACE86532 S62539 AAB27175 NM_005544 NP_005535
Function	May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity). {ECO:0000250}.
Top Pathways	AMPK signaling pathway, cGMP-PKG signaling pathway, Non-alcoholic fatty liver disease (NAFLD), MicroRNAs in cancer, PI3K-Akt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human IRS1 (phospho S307) peptide - ab41770 from Abcam Category Peptide Species Human

Human IRS1 (phospho S636) peptide - ab41771 from Abcam Category Peptide Species Human

Human IRS1 peptide - ab41777 from Abcam Category Peptide Species Human

Human IRS1 peptide - ab41775 from Abcam Category Peptide Species Human

Human IRS1 peptide - ab41776 from Abcam Category Peptide Species Human

Human IRS1 protein fragment - ab70538 from Abcam Category Protein Source Insect cells Species Human

Human IRS1 protein fragment - ab71377 from Abcam Category Protein Source E. coli Species Human

IRS1 (phospho Y896) peptide - ab5224 from Abcam Category Peptide

IRS1 Antibody Blocking Peptide - LS-E30145 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

IRS1 Blocking Peptide - NBP1-77216PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

IRS1 Blocking Peptide - 33R-10758 from Fitzgerald Category Peptide Prices $145.00 Sizes 50 µg

IRS1 (phospho-Ser1101) Blocking Peptide - abx062802 from Abbexa Category Peptide Species Human, Mouse, Rat, Monkey, Pig

IRS1 (phospho-Ser307) Blocking Peptide - abx062803 from Abbexa Category Peptide Species Human, Mouse, Rat, Pig, Monkey

IRS1 Blocking Peptide - abx062804 from Abbexa Category Peptide Species Human, Mouse, Rat, Pig

IRS1 Control Peptide - AP30456CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

IRS1 control peptide - SP5167CP from Acris Antibodies Category Peptide Prices $205.00 Sizes 50 µg

IRS1 control peptide - SP5168CP from Acris Antibodies Category Peptide Prices $205.00 Sizes 50 µg

IRS1 Control Peptide - SP5170CP from Acris Antibodies Category Peptide Prices $205.00 Sizes 50 µg

IRS1 Control Peptide - SP5171CP from Acris Antibodies Category Peptide Prices $205.00 Sizes 35 µg

IRS1 Control Peptide - SP5172CP from Acris Antibodies Category Peptide Prices $205.00 Sizes 50 µg

IRS1 control peptide - SP5173CP from Acris Antibodies Category Peptide Prices $205.00 Sizes 50 µg

Recombinant Human IRS1 C-terminal, Transfected HEK293 Cell Lysate - 230-10080-100 from RayBiotech Category Protein Prices $153.50 Sizes 100 µg Source Human Embryonic Kidney 293 (HEK293) Cells Species Human

Recombinant Human IRS1 C-terminal, Transfected HEK293 Cell Culture Supernatant - 230-20049-200 from RayBiotech Category Protein Prices $102.00 Sizes 200 µl Source Human Embryonic Kidney 293 (HEK293) Cells Species Human

IRS-1 Peptide - 3521P from ProSci Category Peptide Species Human

IRS1 fusion protein - Ag11872 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

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