| Gene Symbol |
HINT2
|
| Entrez Gene |
84681
|
| Alt Symbol |
HIT-17
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
histidine triad nucleotide binding protein 2
|
| Other Description |
HINT-2|HINT-3|HIT-17kDa|PKCI-1-related HIT protein|histidine triad nucleotide-binding protein 2, mitochondrial|protein kinase C inhibitor-2
|
| Swissprots |
Q5TCW3 Q9BX68
|
| Accessions |
AAM09526 EAW58331 EAW58332 EAW58333 EAW58334 Q9BX68 AF085236 AAL40394 AF356515 AAK37562 AF356875 AAM00221 AK222582 BAD96302 AK309795 AY033094 AAK53455 BC033538 BC047737 AAH47737 BI759951 BM764627 HQ448586 ADQ33064 XM_006716880 XP_006716943 XM_011518054 XP_011516356 NM_032593 NP_115982
|
| Function |
Hydrolase probably involved in steroid biosynthesis. May play a role in apoptosis. Has adenosine phosphoramidase activity. {ECO:0000269|PubMed:16762638, ECO:0000269|PubMed:18653718}.
|
| Subcellular Location |
Mitochondrion {ECO:0000269|PubMed:16762638, ECO:0000269|PubMed:18653718}.
|
| Tissue Specificity |
High expression in liver and pancreas. Expression is significantly down-regulated in hepatocellular carcinoma (HCC) patients. {ECO:0000269|PubMed:16762638}.
|
![Western Blot: HINT2 Overexpression Lysate (Adult Normal) [NBL1-11546] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for HINT2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9181_HINT2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-11546-img0002.jpg)