Gene Symbol | HINT2 |
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Entrez Gene | 84681 |
Alt Symbol | HIT-17 |
Species | Human |
Gene Type | protein-coding |
Description | histidine triad nucleotide binding protein 2 |
Other Description | HINT-2|HINT-3|HIT-17kDa|PKCI-1-related HIT protein|histidine triad nucleotide-binding protein 2, mitochondrial|protein kinase C inhibitor-2 |
Swissprots | Q5TCW3 Q9BX68 |
Accessions | AAM09526 EAW58331 EAW58332 EAW58333 EAW58334 Q9BX68 AF085236 AAL40394 AF356515 AAK37562 AF356875 AAM00221 AK222582 BAD96302 AK309795 AY033094 AAK53455 BC033538 BC047737 AAH47737 BI759951 BM764627 HQ448586 ADQ33064 XM_006716880 XP_006716943 XM_011518054 XP_011516356 NM_032593 NP_115982 |
Function | Hydrolase probably involved in steroid biosynthesis. May play a role in apoptosis. Has adenosine phosphoramidase activity. {ECO:0000269|PubMed:16762638, ECO:0000269|PubMed:18653718}. |
Subcellular Location | Mitochondrion {ECO:0000269|PubMed:16762638, ECO:0000269|PubMed:18653718}. |
Tissue Specificity | High expression in liver and pancreas. Expression is significantly down-regulated in hepatocellular carcinoma (HCC) patients. {ECO:0000269|PubMed:16762638}. |
Hint2 CRISPR/Cas9 KO Plasmid (h) - sc-413686 from Santa Cruz Biotechnology
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Hint2 HDR Plasmid (h) - sc-413686-HDR from Santa Cruz Biotechnology
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Hint2 Double Nickase Plasmid (h) - sc-413686-NIC from Santa Cruz Biotechnology
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Hint2 Double Nickase Plasmid (h2) - sc-413686-NIC-2 from Santa Cruz Biotechnology
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Hint2 CRISPR Activation Plasmid (h) - sc-413686-ACT from Santa Cruz Biotechnology
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Hint2 CRISPR Activation Plasmid (h2) - sc-413686-ACT-2 from Santa Cruz Biotechnology
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Hint2 Lentiviral Activation Particles (h) - sc-413686-LAC from Santa Cruz Biotechnology
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Hint2 Lentiviral Activation Particles (h2) - sc-413686-LAC-2 from Santa Cruz Biotechnology
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Hint2 siRNA (h) - sc-92707 from Santa Cruz Biotechnology
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Hint2 shRNA Plasmid (h) - sc-92707-SH from Santa Cruz Biotechnology
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Hint2 shRNA (h) Lentiviral Particles - sc-92707-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN10040 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10040 from Sigma-Aldrich
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HINT2 siRNA (Human) - CRJ3578 from Cohesion Biosciences
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HINT2 RNAi - H00084681-R01 from Novus Biologicals
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HINT2 - MBS8220611 from MyBioSource
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shRNA set against Human HINT2 (NM_032593.2) - SHH312233 from Creative biogene
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shRNA set against Human HINT2(NM_032593.2) - SHH120935 from Creative biogene
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Human HINT2 siRNA - orb274079 from Biorbyt
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HINT2 shRNA Plasmid (Human) - CHJ3578 from Cohesion Biosciences
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HINT2 miRNA 3'UTR clone - MiUTR1H-04504 from Creative biogene
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