| Gene Symbol |
FAM109A
|
| Entrez Gene |
144717
|
| Alt Symbol |
IPIP27A, SES1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
family with sequence similarity 109, member A
|
| Other Description |
27 kDa inositol polyphosphate phosphatase-interacting protein A|protein FAM109A|sesquipedalian-1
|
| Swissprots |
Q96MH8 J3KP50 Q6PJL9 Q8N4B1
|
| Accessions |
EAW97950 Q8N4B1 AK056918 BAB71310 AK093052 BAC04036 AK299344 BAG61345 BC014091 AAH14091 BC018996 BC034809 AAH34809 CX758147 CX785083 DA707326 DB055268 XM_006719257 XP_006719320 XM_011537976 XP_011536278 NM_001177996 NP_001171467 NM_001177997 NP_001171468 NM_144671 NP_653272
|
| Function |
Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane. {ECO:0000269|PubMed:21233288}.
|
| Subcellular Location |
Early endosome. Recycling endosome. Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle, clathrin- coated vesicle. Note=Interaction with OCRL may be crucial for targeting to endosome and to the trans-Golgi network. Also found on macropinosomes. Not detected in late endosomes, nor in lysosomes.
|
![Western Blot: FAM109A Overexpression Lysate (Adult Normal) [NBL1-10441] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for FAM109A.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/10592_FAM109A%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-10441-img0002.jpg)