Gene Symbol | FAM109A |
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Entrez Gene | 144717 |
Alt Symbol | IPIP27A, SES1 |
Species | Human |
Gene Type | protein-coding |
Description | family with sequence similarity 109, member A |
Other Description | 27 kDa inositol polyphosphate phosphatase-interacting protein A|protein FAM109A|sesquipedalian-1 |
Swissprots | Q96MH8 J3KP50 Q6PJL9 Q8N4B1 |
Accessions | EAW97950 Q8N4B1 AK056918 BAB71310 AK093052 BAC04036 AK299344 BAG61345 BC014091 AAH14091 BC018996 BC034809 AAH34809 CX758147 CX785083 DA707326 DB055268 XM_006719257 XP_006719320 XM_011537976 XP_011536278 NM_001177996 NP_001171467 NM_001177997 NP_001171468 NM_144671 NP_653272 |
Function | Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane. {ECO:0000269|PubMed:21233288}. |
Subcellular Location | Early endosome. Recycling endosome. Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle, clathrin- coated vesicle. Note=Interaction with OCRL may be crucial for targeting to endosome and to the trans-Golgi network. Also found on macropinosomes. Not detected in late endosomes, nor in lysosomes. |
FAM109A CRISPR/Cas9 KO Plasmid (h) - sc-417438 from Santa Cruz Biotechnology
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FAM109A HDR Plasmid (h) - sc-417438-HDR from Santa Cruz Biotechnology
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FAM109A Double Nickase Plasmid (h) - sc-417438-NIC from Santa Cruz Biotechnology
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FAM109A Double Nickase Plasmid (h2) - sc-417438-NIC-2 from Santa Cruz Biotechnology
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FAM109A CRISPR Activation Plasmid (h) - sc-417438-ACT from Santa Cruz Biotechnology
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FAM109A CRISPR Activation Plasmid (h2) - sc-417438-ACT-2 from Santa Cruz Biotechnology
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FAM109A Lentiviral Activation Particles (h) - sc-417438-LAC from Santa Cruz Biotechnology
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FAM109A Lentiviral Activation Particles (h2) - sc-417438-LAC-2 from Santa Cruz Biotechnology
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FAM109A siRNA (h) - sc-95958 from Santa Cruz Biotechnology
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FAM109A shRNA Plasmid (h) - sc-95958-SH from Santa Cruz Biotechnology
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FAM109A shRNA (h) Lentiviral Particles - sc-95958-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU151601 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8121 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8121 from Sigma-Aldrich
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FAM109A siRNA (Human) - CRJ5419 from Cohesion Biosciences
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FAM109A - MBS8204373 from MyBioSource
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shRNA set against Human FAM109A (NM_144671.4) - SHH289065 from Creative biogene
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FAM109A shRNA Plasmid (Human) - CHJ5419 from Cohesion Biosciences
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FAM109A miRNA 3'UTR clone - MiUTR4H-TG03339 from Creative biogene
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