Gene Symbol | GIF |
---|---|
Entrez Gene | 2694 |
Alt Symbol | IF, IFMH, INF, TCN3 |
Species | Human |
Gene Type | protein-coding |
Description | gastric intrinsic factor (vitamin B synthesis) |
Other Description | gastric intrinsic factor|intrinsic factor |
Swissprots | B4DVZ1 P27352 B2RAN8 |
Accessions | EAW73860 P27352 AK301290 BAG62848 AK301295 BAG62853 AK314275 BAG36935 BC037958 AAH37958 DQ892469 ABM83395 DQ895682 ABM86608 X76562 CAA54061 XM_011544939 XP_011543241 NM_005142 NP_005133 |
Function | Promotes absorption of the essential vitamin cobalamin (Cbl) in the ileum. After interaction with CUBN, the GIF-cobalamin complex is internalized via receptor-mediated endocytosis. |
Subcellular Location | Secreted. |
Tissue Specificity | Gastric mucosa. |
Top Pathways | Vitamin digestion and absorption |