| Gene Symbol |
SEPT1
|
| Entrez Gene |
1731
|
| Alt Symbol |
DIFF6, LARP, PNUTL3, SEP1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
septin 1
|
| Other Description |
differentiation 6 (deoxyguanosine triphosphate triphosphohydrolase)|peanut-like protein 3|septin-1|serologically defined breast cancer antigen NY-BR-24
|
| Swissprots |
Q8WYJ6 Q8NEZ1 B4DVE6 Q9H285 Q658T1 Q96EL4
|
| Accessions |
AAG48256 EAW52252 EAW52253 Q8WYJ6 AF085235 AAL40393 AK301045 BAG62658 AK303390 BAG64446 AL833004 CAH56484 AY034176 AAK61491 BC012161 AAH12161 BM663465 BQ072902 NM_052838 NP_443070
|
| Function |
Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). {ECO:0000250, ECO:0000305}.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Note=Remains at the centrosomes and the nearby microtubules throughout mitosis. Localizes to the midbody during cytokinesis.
|
| Tissue Specificity |
Expressed at high levels in lymphoid and hematopoietic tissues. {ECO:0000269|PubMed:15915442}.
|
| Top Pathways |
Bacterial invasion of epithelial cells
|