Gene Symbol | SEPT1 |
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Entrez Gene | 1731 |
Alt Symbol | DIFF6, LARP, PNUTL3, SEP1 |
Species | Human |
Gene Type | protein-coding |
Description | septin 1 |
Other Description | differentiation 6 (deoxyguanosine triphosphate triphosphohydrolase)|peanut-like protein 3|septin-1|serologically defined breast cancer antigen NY-BR-24 |
Swissprots | Q8WYJ6 Q8NEZ1 B4DVE6 Q9H285 Q658T1 Q96EL4 |
Accessions | AAG48256 EAW52252 EAW52253 Q8WYJ6 AF085235 AAL40393 AK301045 BAG62658 AK303390 BAG64446 AL833004 CAH56484 AY034176 AAK61491 BC012161 AAH12161 BM663465 BQ072902 NM_052838 NP_443070 |
Function | Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). {ECO:0000250, ECO:0000305}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Note=Remains at the centrosomes and the nearby microtubules throughout mitosis. Localizes to the midbody during cytokinesis. |
Tissue Specificity | Expressed at high levels in lymphoid and hematopoietic tissues. {ECO:0000269|PubMed:15915442}. |
Top Pathways | Bacterial invasion of epithelial cells |
Septin 1 CRISPR/Cas9 KO Plasmid (h) - sc-405151 from Santa Cruz Biotechnology
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Septin 1 HDR Plasmid (h) - sc-405151-HDR from Santa Cruz Biotechnology
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Septin 1 Double Nickase Plasmid (h) - sc-405151-NIC from Santa Cruz Biotechnology
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Septin 1 Double Nickase Plasmid (h2) - sc-405151-NIC-2 from Santa Cruz Biotechnology
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Septin 1 CRISPR Activation Plasmid (h) - sc-405151-ACT from Santa Cruz Biotechnology
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Septin 1 CRISPR Activation Plasmid (h2) - sc-405151-ACT-2 from Santa Cruz Biotechnology
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Septin 1 Lentiviral Activation Particles (h) - sc-405151-LAC from Santa Cruz Biotechnology
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Septin 1 Lentiviral Activation Particles (h2) - sc-405151-LAC-2 from Santa Cruz Biotechnology
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Septin 1 siRNA (h) - sc-36472 from Santa Cruz Biotechnology
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Septin 1 shRNA Plasmid (h) - sc-36472-SH from Santa Cruz Biotechnology
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Septin 1 shRNA (h) Lentiviral Particles - sc-36472-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU024641 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19098 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19098 from Sigma-Aldrich
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SEPT1 siRNA (Human) - CRH1200 from Cohesion Biosciences
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SEPT1 - MBS8223908 from MyBioSource
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Human SEPT1 siRNA - orb261702 from Biorbyt
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SEPT1 shRNA Plasmid (Human) - CHH1200 from Cohesion Biosciences
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