WDR45

Gene Symbol WDR45
Entrez Gene 11152
Alt Symbol JM5, NBIA4, NBIA5, WDRX1, WIPI-4, WIPI4
Species Human
Gene Type protein-coding
Description WD repeat domain 45
Other Description WD repeat domain phosphoinositide-interacting protein 4|WD repeat domain, X-linked 1|WD repeat-containing protein 45|WD45 repeat protein interacting with phosphoinositides 4|neurodegeneration with brain iron accumulation 4|neurodegeneration with brain iron accumulation 5
Swissprots Q6NT94 Q6IBS7 Q9Y484 B7WPI2 Q96H03 Q5MNZ5 A6NGH5
Accessions EAW50695 EAW50696 EAW50697 EAW50698 EAW50699 EAW50700 EAW50701 EAW50702 EAW50703 EAW50704 Q9Y484 AJ005897 CAA06754 AK023344 AK225122 AK301084 BAG62688 AK315717 AY691428 AAV80764 BC000464 AAH00464 BC003037 AAH03037 BC009027 AAH09027 BC035979 BC069206 AAH69206 BQ068083 CR456725 CAG33006 DQ892245 ABM83171 DQ895446 ABM86372 NM_001029896 NP_001025067 NM_007075 NP_009006
Function Plays an important role in the autophagy pathway, which is the major intracellular degradation system by which cytoplasmic materials are packaged into autophagosomes and delivered to lysosomes for degradation. {ECO:0000269|PubMed:23435086}.
Tissue Specificity Ubiquitously expressed, with high expression in skeletal muscle and heart. Weakly expressed in liver and placenta. Expression is down-regulated in pancreatic and in kidney tumors. {ECO:0000269|PubMed:15602573}.

WIPI-4 (G-12) - sc-398272 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
WIPI-4 (G-12): sc-398272. Western blot analysis of WIPI-4 expression in non-transfected 293T: sc-117752 (A), mouse WIPI-4 transfected 293T: sc-124647 (B) and A549 (C) whole cell lysates.

WIPI-4 (A-17) - sc-83074 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

WIPI-4 (C-20) - sc-83075 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

WIPI-4 (K-20) - sc-83076 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
WIPI-4 (K-20): sc-83076. Western blot analysis of WIPI-4 expression in non-transfected: sc-117752 (A) and mouse WIPI-4 transfected: sc-124647 (B) 293T whole cell lysates.

Anti-WDR45 antibody - ab168532 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Immunofluorescence analysis of HeLa cells, labeling WDR45 with ab168532 at 10&microg/ml.

Anti-WDR45 antibody - ab176994 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical staining of formalin-fixed, paraffin-embedded Human fetal liver tissue labeling WDR45 with ab176994 at 1/100 dilution showing cytoplasmic staining.

Anti-WDR45 antibody - N-terminal - ab171669 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-WDR45 antibody - N-terminal (ab171669) at 1/100 dilution + A549 cell line lysates at 35 µg/ml

Anti-WDR45 Antibody (aa17-46, AP) - LS-C273511 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-WDR45 Antibody (aa17-46, APC) - LS-C273512 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-WDR45 Antibody (aa17-46, Biotin) - LS-C273513 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-WDR45 Antibody (aa17-46, FITC) - LS-C273514 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-WDR45 Antibody (aa17-46, Azide-free, HRP) - LS-C273515 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-WDR45 Antibody (aa17-46, PE) - LS-C273517 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-WDR45 Antibody (aa16-46) - LS-C326335 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-WDR45 Antibody (aa17-46) - LS-C157366 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
WDR45 Antibody western blot of A549 cell line lysates (35 ug/lane). The WDR45 antibody detected the WDR45 protein (arrow).

WDR45 Antibody - H00011152-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: WDR45 Antibody [H00011152-B01P] - Analysis of WDR45 expression in transfected 293T cell line by WDR45 polyclonal antibody. Lane 1: WDR45 transfected lysate(39.71 KDa). Lane 2: Non-transfected lysate.

Anti-WDR45 (229-240) antibody produced in rabbit - SAB1101582 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human WDR45 was separated on SDS-PAGE, blotted with Anti-WDR45 (229-240) (<B>Cat. No. SAB1101582</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate. <BR/><B>Lanes</B><BR/>1. Antibody dilution 1:500

Anti-WDR45 antibody produced in mouse - SAB1400421 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Polyclonal Anti-WDR45, antibody produced in mouse, purified immunoglobulin: <B>Cat. No. SAB1400421</B>: Antibody concentration: 1.0 μg/mL using HeLa cells.

Anti-WDR45 (131-145) antibody produced in rabbit - SAB1101581 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-WDR45 (131-145) (RB): <B>Cat. No. SAB1101581</B>: Immunofluorescence of HUVEC cells using Anti-WDR45 (131-145) (RB) at a 1:200 dilution, taken at 40× magnification and nuclear staining with Hoescht 33342 (blue). Yale HTCB IF procedure used. Images may have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

WDR45-Antibody-N-term - AP13313a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Anti-WDR45 Antibody (N-term) at 1:1000 dilution + human heart lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 40 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

WDR45 Antibody - N-terminal region (OAAB09622) - OAAB09622 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

WDR45 antibody - 70R-21311 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

WDR45 Antibody - abx036037 from Abbexa

Host Rabbit
Clonality Polyclonal

WDR45 Antibody - abx027335 from Abbexa

Host Rabbit
Clonality Polyclonal

WDR45 / WIPI-4 antibody - 19194-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical of paraffin-embedded human liver using 19194-1-AP(WDR45 antibody) at dilution of 1:50 (under 10x lens)
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