WDR45

Gene Symbol	WDR45
Entrez Gene	11152
Alt Symbol	JM5, NBIA4, NBIA5, WDRX1, WIPI-4, WIPI4
Species	Human
Gene Type	protein-coding
Description	WD repeat domain 45
Other Description	WD repeat domain phosphoinositide-interacting protein 4|WD repeat domain, X-linked 1|WD repeat-containing protein 45|WD45 repeat protein interacting with phosphoinositides 4|neurodegeneration with brain iron accumulation 4|neurodegeneration with brain iron accumulation 5
Swissprots	Q6NT94 Q6IBS7 Q9Y484 B7WPI2 Q96H03 Q5MNZ5 A6NGH5
Accessions	EAW50695 EAW50696 EAW50697 EAW50698 EAW50699 EAW50700 EAW50701 EAW50702 EAW50703 EAW50704 Q9Y484 AJ005897 CAA06754 AK023344 AK225122 AK301084 BAG62688 AK315717 AY691428 AAV80764 BC000464 AAH00464 BC003037 AAH03037 BC009027 AAH09027 BC035979 BC069206 AAH69206 BQ068083 CR456725 CAG33006 DQ892245 ABM83171 DQ895446 ABM86372 NM_001029896 NP_001025067 NM_007075 NP_009006
Function	Plays an important role in the autophagy pathway, which is the major intracellular degradation system by which cytoplasmic materials are packaged into autophagosomes and delivered to lysosomes for degradation. {ECO:0000269|PubMed:23435086}.
Tissue Specificity	Ubiquitously expressed, with high expression in skeletal muscle and heart. Weakly expressed in liver and placenta. Expression is down-regulated in pancreatic and in kidney tumors. {ECO:0000269|PubMed:15602573}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

WIPI-4 CRISPR/Cas9 KO Plasmid (h) - sc-407357 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

WIPI-4 HDR Plasmid (h) - sc-407357-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

WIPI-4 Double Nickase Plasmid (h) - sc-407357-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

WIPI-4 Double Nickase Plasmid (h2) - sc-407357-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

WIPI-4 CRISPR Activation Plasmid (h) - sc-407357-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

WIPI-4 CRISPR Activation Plasmid (h2) - sc-407357-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

WIPI-4 Lentiviral Activation Particles (h) - sc-407357-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

WIPI-4 Lentiviral Activation Particles (h2) - sc-407357-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

WIPI-4 siRNA (h) - sc-72216 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

WIPI-4 shRNA Plasmid (h) - sc-72216-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

WIPI-4 shRNA (h) Lentiviral Particles - sc-72216-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU103641 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

MISSION® esiRNA - EHU023161 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22828 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22828 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02949 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr02949

WDR45 siRNA (Human) - CRH7633 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

WDR45 - MBS8237439 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human WDR45 (NM_007075.3) - SHH446192 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human WDR45(NM_001029896.1) - SHL131500 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human WDR45(NM_007075.3) - SHL131520 from Creative biogene Category siRNA Species Reactivities Human

Human WDR45 siRNA - orb268135 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

WDR45 shRNA Plasmid (Human) - CHH7633 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

WDR45 miRNA 3'UTR clone - MiUTR1H-11216 from Creative biogene Species Reactivities Human

WDR45 miRNA 3'UTR clone - MiUTR1H-11217 from Creative biogene Species Reactivities Human

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