| Gene Symbol |
NPBWR1
|
| Entrez Gene |
2831
|
| Alt Symbol |
GPR7
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
neuropeptides B/W receptor 1
|
| Other Description |
G protein-coupled receptor 7|G-protein coupled receptor 7|neuropeptide B/W receptor 1|neuropeptides B/W receptor type 1|opioid-somatostatin-like receptor 7
|
| Swissprots |
Q6NTC7 P48145
|
| Accessions |
AAC50197 AFF59482 EAW86722 P48145 BC069117 AAH69117 BC107101 AAI07102 NM_005285 NP_005276
|
| Function |
Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Has a higher affinity for neuropeptide B.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Found in cerebellum and frontal cortex. Detected at high levels in hippocampus, amygdala and trachea; at moderate levels in fetal brain, pituitary gland and prostate. Not in caudate, accumbens, kidney or liver. Also detected at high levels in lung carcinoma. {ECO:0000269|PubMed:12401809}.
|
| Top Pathways |
Neuroactive ligand-receptor interaction
|
![Western Blot: NPBWR1 Overexpression Lysate (Adult Normal) [NBL1-13741] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for NPBWR1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6460_NPBWR1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-13741-img0002.jpg)