| Gene Symbol |
MARCH3
|
| Entrez Gene |
115123
|
| Alt Symbol |
MARCH-III, RNF173
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase
|
| Other Description |
E3 ubiquitin-protein ligase MARCH3|RING finger protein 173|membrane-associated RING-CH protein III
|
| Swissprots |
B9EJE7 A8K264 Q86UD3
|
| Accessions |
EAW48844 Q86UD3 AF055007 AK000103 AK290129 BAF82818 BC047569 AAH47569 BC146948 AAI46949 BC146964 AAI46965 BG719261 DB455278 XM_011543128 XP_011541430 XM_011543129 XP_011541431 XM_011543130 XP_011541432 XM_011543131 XP_011541433 XM_011543132 XP_011541434 XM_011543133 XP_011541435 XR_948234 NM_178450 NP_848545
|
| Function |
E3 ubiquitin-protein ligase which may be involved in endosomal trafficking. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasmic vesicle membrane {ECO:0000269|PubMed:16428329}; Multi-pass membrane protein {ECO:0000269|PubMed:16428329}. Early endosome membrane {ECO:0000269|PubMed:16428329}; Multi-pass membrane protein {ECO:0000269|PubMed:16428329}.
|
![Western Blot: MARCH3 Overexpression Lysate (Adult Normal) [NBL1-06999] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for MARCH3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7555_MARCH3%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-06999-img0002.jpg)