| Gene Symbol |
BCDIN3D
|
| Entrez Gene |
144233
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
BCDIN3 domain containing
|
| Other Description |
BCDIN3 domain-containing protein|pre-miRNA 5'-monophosphate methyltransferase|probable methyltransferase BCDIN3D
|
| Swissprots |
A8K829 Q7Z5W3
|
| Accessions |
EAW58101 Q7Z5W3 AK292194 BAF84883 BC040957 BC053560 AAH53560 BU622810 CD690663 HQ448096 ADQ32577 NM_181708 NP_859059
|
| Function |
O-methyltransferase that specifically dimethylates the 5' monophosphate of pre-miRNAs, acting as a negative regulator of miRNA processing. The 5' monophosphate of pre-miRNAs is recognized by DICER1 and is required for pre-miRNAs processing: methylation at this position reduces the processing of pre-miRNAs by DICER1. Able to mediate methylation of pre-miR-145, as well as other pre- miRNAs. {ECO:0000269|PubMed:23063121}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:23063121}.
|