Gene Symbol |
NUPL2
|
Entrez Gene |
11097
|
Alt Symbol |
CG1, NLP-1, NLP_1, hCG1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
nucleoporin like 2
|
Other Description |
H_RG271G13.9|NUP42 homolog|nucleoporin hCG1|nucleoporin-like protein 1|nucleoporin-like protein 2
|
Swissprots |
B4DP42 O15504 A4D143 Q49AE7 Q9BS49
|
Accessions |
EAL24260 EAW93775 EAW93776 EAW93777 EAW93778 EAW93779 O15504 AI352214 AK124359 AK298183 BAG60454 AK300113 BAG61908 AK312991 BAG35828 BC005327 AAH05327 BC039333 AAH39333 BC107583 AAI07584 BT007409 AAP36077 DC398445 U97198 AAC33794 XM_005249592 XP_005249649 XM_005249593 XP_005249650 XM_011515104 XP_011513406 XR_926913 NM_007342 NP_031368
|
Function |
Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. In case of infection by HIV-1, it may participate in the docking of viral Vpr at the nuclear envelope. {ECO:0000269|PubMed:10610322, ECO:0000269|PubMed:16000379}.
|
Subcellular Location |
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Excluded from the nucleolus.
|
Tissue Specificity |
Ubiquitously expressed. {ECO:0000269|PubMed:10358091}.
|
Top Pathways |
RNA transport
|