Gene Symbol | NUPL2 |
---|---|
Entrez Gene | 11097 |
Alt Symbol | CG1, NLP-1, NLP_1, hCG1 |
Species | Human |
Gene Type | protein-coding |
Description | nucleoporin like 2 |
Other Description | H_RG271G13.9|NUP42 homolog|nucleoporin hCG1|nucleoporin-like protein 1|nucleoporin-like protein 2 |
Swissprots | B4DP42 O15504 A4D143 Q49AE7 Q9BS49 |
Accessions | EAL24260 EAW93775 EAW93776 EAW93777 EAW93778 EAW93779 O15504 AI352214 AK124359 AK298183 BAG60454 AK300113 BAG61908 AK312991 BAG35828 BC005327 AAH05327 BC039333 AAH39333 BC107583 AAI07584 BT007409 AAP36077 DC398445 U97198 AAC33794 XM_005249592 XP_005249649 XM_005249593 XP_005249650 XM_011515104 XP_011513406 XR_926913 NM_007342 NP_031368 |
Function | Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. In case of infection by HIV-1, it may participate in the docking of viral Vpr at the nuclear envelope. {ECO:0000269|PubMed:10610322, ECO:0000269|PubMed:16000379}. |
Subcellular Location | Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Excluded from the nucleolus. |
Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:10358091}. |
Top Pathways | RNA transport |
NupL2 CRISPR/Cas9 KO Plasmid (h) - sc-411565 from Santa Cruz Biotechnology
|
||||||||
NupL2 HDR Plasmid (h) - sc-411565-HDR from Santa Cruz Biotechnology
|
||||||||
NupL2 Double Nickase Plasmid (h) - sc-411565-NIC from Santa Cruz Biotechnology
|
||||||||
NupL2 Double Nickase Plasmid (h2) - sc-411565-NIC-2 from Santa Cruz Biotechnology
|
||||||||
NupL2 CRISPR Activation Plasmid (h) - sc-411565-ACT from Santa Cruz Biotechnology
|
||||||||
NupL2 CRISPR Activation Plasmid (h2) - sc-411565-ACT-2 from Santa Cruz Biotechnology
|
||||||||
NupL2 Lentiviral Activation Particles (h) - sc-411565-LAC from Santa Cruz Biotechnology
|
||||||||
NupL2 Lentiviral Activation Particles (h2) - sc-411565-LAC-2 from Santa Cruz Biotechnology
|
||||||||
NupL2 siRNA (h) - sc-89655 from Santa Cruz Biotechnology
|
||||||||
NupL2 shRNA Plasmid (h) - sc-89655-SH from Santa Cruz Biotechnology
|
||||||||
NupL2 shRNA (h) Lentiviral Particles - sc-89655-V from Santa Cruz Biotechnology
|
||||||||
NUPL2 RNAi - H00011097-R01 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU067171 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN15639 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15639 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR02426 from Sigma-Aldrich
|
||||||||
NUPL2 siRNA (Human) - CRH7589 from Cohesion Biosciences
|
||||||||
shRNA set against Human NUPL2 (NM_007342.2) - SHH356600 from Creative biogene
|
||||||||
Human NUPL2 siRNA - orb268091 from Biorbyt
|
||||||||
NUPL2 shRNA Plasmid (Human) - CHH7589 from Cohesion Biosciences
|
||||||||
NUPL2 miRNA 3'UTR clone - MiUTR3H-15627 from Creative biogene
|