Gene Symbol |
NQO2
|
Entrez Gene |
4835
|
Alt Symbol |
DHQV, DIA6, NMOR2, QR2
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
NAD(P)H dehydrogenase, quinone 2
|
Other Description |
NAD(P)H menadione oxidoreductase-1, dioxin-inducible-2|NRH:quinone oxidoreductase 2|quinone reductase 2|ribosyldihydronicotinamide dehydrogenase|ribosyldihydronicotinamide dehydrogenase [quinone]
|
Swissprots |
B2R492 Q5TD04 P16083
|
Accessions |
AAB60642 AAW29945 BAB16974 CAJ42720 EAW55107 EAW55108 EAW55109 EAW55110 EAW55111 P16083 AK056981 BAG51838 AK097187 AK311746 BAG34689 BC006096 AAH06096 BI670476 CD014013 J02888 AAA60239 XM_005249148 XP_005249205 XM_005249149 XP_005249206 XM_005249150 XP_005249207 XM_005249151 XP_005249208 XM_006715100 XP_006715163 XM_011514642 XP_011512944 XM_011514643 XP_011512945 XM_011514644 XP_011512946 XM_011514645 XP_011512947 XM_011514646 XP_011512948 NM_000904 NP_000895 NM_001290221 NP_001277150 NM_001290222 NP_001277151
|
Function |
The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. {ECO:0000269|PubMed:18254726}.
|
Subcellular Location |
Cytoplasm.
|