Gene Symbol | NQO2 |
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Entrez Gene | 4835 |
Alt Symbol | DHQV, DIA6, NMOR2, QR2 |
Species | Human |
Gene Type | protein-coding |
Description | NAD(P)H dehydrogenase, quinone 2 |
Other Description | NAD(P)H menadione oxidoreductase-1, dioxin-inducible-2|NRH:quinone oxidoreductase 2|quinone reductase 2|ribosyldihydronicotinamide dehydrogenase|ribosyldihydronicotinamide dehydrogenase [quinone] |
Swissprots | B2R492 Q5TD04 P16083 |
Accessions | AAB60642 AAW29945 BAB16974 CAJ42720 EAW55107 EAW55108 EAW55109 EAW55110 EAW55111 P16083 AK056981 BAG51838 AK097187 AK311746 BAG34689 BC006096 AAH06096 BI670476 CD014013 J02888 AAA60239 XM_005249148 XP_005249205 XM_005249149 XP_005249206 XM_005249150 XP_005249207 XM_005249151 XP_005249208 XM_006715100 XP_006715163 XM_011514642 XP_011512944 XM_011514643 XP_011512945 XM_011514644 XP_011512946 XM_011514645 XP_011512947 XM_011514646 XP_011512948 NM_000904 NP_000895 NM_001290221 NP_001277150 NM_001290222 NP_001277151 |
Function | The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. {ECO:0000269|PubMed:18254726}. |
Subcellular Location | Cytoplasm. |
NQO2 CRISPR/Cas9 KO Plasmid (h) - sc-402200 from Santa Cruz Biotechnology
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NQO2 HDR Plasmid (h) - sc-402200-HDR from Santa Cruz Biotechnology
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NQO2 Double Nickase Plasmid (h) - sc-402200-NIC from Santa Cruz Biotechnology
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NQO2 Double Nickase Plasmid (h2) - sc-402200-NIC-2 from Santa Cruz Biotechnology
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NQO2 CRISPR Activation Plasmid (h) - sc-402200-ACT from Santa Cruz Biotechnology
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NQO2 CRISPR Activation Plasmid (h2) - sc-402200-ACT-2 from Santa Cruz Biotechnology
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NQO2 Lentiviral Activation Particles (h) - sc-402200-LAC from Santa Cruz Biotechnology
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NQO2 Lentiviral Activation Particles (h2) - sc-402200-LAC-2 from Santa Cruz Biotechnology
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NQO2 siRNA (h) - sc-41575 from Santa Cruz Biotechnology
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NQO2 shRNA Plasmid (h) - sc-41575-SH from Santa Cruz Biotechnology
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NQO2 shRNA (h) Lentiviral Particles - sc-41575-V from Santa Cruz Biotechnology
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NQO-2 RNAi - H00004835-R01 from Novus Biologicals
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MISSION® esiRNA - EHU074261 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15484 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15484 from Sigma-Aldrich
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NQO2 siRNA (Human) - CRH3211 from Cohesion Biosciences
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shRNA set against Human NQO2 (NM_000904.3) - SHH354600 from Creative biogene
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shRNA set against Human NQO2(NM_000904.3) - SHR019222 from Creative biogene
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NQO2 shRNA Plasmid (Human) - CHH3211 from Cohesion Biosciences
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NQO2 miRNA 3'UTR clone - MiUTR1H-06891 from Creative biogene
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