CD59

Gene Symbol	CD59
Entrez Gene	966
Alt Symbol	16.3A5, 1F5, EJ16, EJ30, EL32, G344, HRF-20, HRF20, MAC-IP, MACIF, MEM43, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, p18-20
Species	Human
Gene Type	protein-coding
Description	CD59 molecule, complement regulatory protein
Other Description	1F5 antigen|20 kDa homologous restriction factor|CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344)|CD59 glycoprotein|Ly-6-like protein|MEM43 antigen|T cell-activating protein|human leukocyte antigen MIC11|lymphocytic antigen CD59/MEM43|membrane attack complex (MAC) inhibition factor|membrane attack complex inhibition factor|membrane inhibitor of reactive lysis|protectin|surface anitgen recognized by monoclonal antibody 16.3A5
Swissprots	P13987
Accessions	AAA88793 CAA78486 EAW68192 EAW68193 P13987 AI147924 AK128571 AK309894 AK311778 BAG34721 AL037045 AL049957 AL080087 AL703204 AU136899 AU139009 AU139541 AW166662 BC001506 AAH01506 BC033226 BE899630 BG284181 BI752924 BM457931 BM551313 BM680161 BM724931 BM829941 BM911556 BQ230563 BQ440441 BT007104 AAP35768 BU154979 BX475103 CF529941 CR407661 CAG28589 CR541722 CAG46523 DA250543 DA578905 DA840870 DA917093 DQ890640 ABM92257 DQ893818 ABM84744 EU176474 ABW03275 M27909 AAA60543 M34671 AAA51952 M95708 AAA60957 X16447 CAA34467 X17198 CAA35059 X84805 NM_000611 NP_000602 NM_001127223 NP_001120695 NM_001127225 NP_001120697 NM_001127226 NP_001120698 NM_001127227 NP_001120699 NM_203329 NP_976074 NM_203330 NP_976075 NM_203331 NP_976076
Function	Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.
Subcellular Location	Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Note=Soluble form found in a number of tissues.
Top Pathways	Complement and coagulation cascades, Hematopoietic cell lineage

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CD59 ELISA Kit (Sandwich ELISA) - LS-F6544 from LifeSpan Bioscience Category ELISA Kit Prices $690.00 Sizes 1 plate Sensitivity 12.5 pg/ml Range 40.96-4000 pg/ml

Mouse CD59 ELISA Kit (Sandwich ELISA) - LS-F9560 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 25.5 pg/ml Range 40.96-4000 pg/ml

Human CD59 ELISA Kit (Sandwich ELISA) - LS-F11090 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 31.2 Range 40.96-4000 pg/ml

Rat CD59 ELISA Kit (Sandwich ELISA) - LS-F11089 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 Range 40.96-4000 pg/ml

Human CD59 ELISA kit - orb196650 from Biorbyt Category ELISA Kit Prices $859.00, $1,471.00, $3,154.00 Sizes 96 assays, 192 assays, 480 assays

Human Protectin ELISA Kit - abx152853 from Abbexa Category ELISA Kit Sensitivity 5.1 pg/ml Range 12.5 pg/ml - 800 pg/ml

Protectin, CD59, Human, ELISA Kit - E-EL-H0682 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 18.75 Range 31.25-2000pg/mL

CD59 glycoprotein (CD59), Human, ELISA Kit - CSB-EL004947HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 3.9 pg/ml Range 15.6 pg/ml-1000 pg/ml

CD59 glycoprotein (CD59), Human, ELISA Kit - E01C1490 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

CD59 glycoprotein, CD59, Human, ELISA Kit - E2116h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 31.2-2000 pg/mL

Protectin (CD59), Human, ELISA Kit - SEB336Hu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Sensitivity 13.7pg/mL Range 31.2-2,000pg/mL

Protectin, Human, ELISA Kit - E01P0352 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 1.0pg/ml Range 25-500pg/ml

Protectin, CD59, Rabbit, ELISA Kit - E-EL-RB1332 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Protectin, CD59, Chicken, ELISA Kit - E-EL-Ch0668 from ARP American Research Products Category ELISA Kit Prices $504.00 Sizes 96 t

Protectin, CD59, Porcine, ELISA Kit - E-EL-P0217 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Protectin, CD59, Sheep, ELISA Kit - E-EL-S0788 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Protectin, CD59, Guinea Pig, ELISA Kit - E-EL-GP1302 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Protectin, CD59, Monkey, ELISA Kit - E-EL-MK0938 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Human CD 59 ELISA - ELH-CD59 from RayBiotech Category ELISA Kit Prices $462.00, $832.00, $1,850.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit Sensitivity 40 pg/ml Range 40 pg/ml - 10,000 pg/ml

Human CD59 ELISA Kit - HP0359 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine CD59 ELISA Kit - AP0359 from NeoScientific Category ELISA Kit Prices $300.00, $480.00 Sizes 100 µl, 200 µl

Human CD59(Protectin) ELISA Kit - E-EL-H0682 from Elabscience Category ELISA Kit Sensitivity 18.75 pg/mL Range 31.25—2000 pg/mL

Human CD59 (Protectin) CLIA Kit - E-CL-H0510 from Elabscience Category CLIA Kit Sensitivity 9.38 pg/mL Range Average Recovery (%)

CD59, ELISA Kit - MBS2504754 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 18.75pg/mL Range 31.25--2000pg/mL

CD59, ELISA Kit - MBS2515522 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.938pg/mL Range 1.563-100pg/mL

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