| Gene Symbol | CLDN3 |
|---|---|
| Entrez Gene | 1365 |
| Alt Symbol | C7orf1, CPE-R2, CPETR2, HRVP1, RVP1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | claudin 3 |
| Other Description | CPE-R 2|CPE-receptor 2|Clostridium perfringens enterotoxin receptor 2|claudin-3|ventral prostate.1 protein homolog|ventral prostate.1-like protein |
| Swissprots | O15551 |
| Accessions | AAC78277 AAS07555 CAI29151 EAW69641 O15551 AB000714 BAA22986 AK313276 BAG36084 BC009083 BC016056 AAH16056 BM764277 DQ892211 ABM83137 EU176670 ABW03471 NM_001306 NP_001297 |
| Function | Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. {ECO:0000250}. |
| Subcellular Location | Cell junction, tight junction {ECO:0000250}. Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
| Top Pathways | Tight junction, Leukocyte transendothelial migration, Cell adhesion molecules (CAMs), Hepatitis C |