Gene Symbol |
CLDN3
|
Entrez Gene |
1365
|
Alt Symbol |
C7orf1, CPE-R2, CPETR2, HRVP1, RVP1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
claudin 3
|
Other Description |
CPE-R 2|CPE-receptor 2|Clostridium perfringens enterotoxin receptor 2|claudin-3|ventral prostate.1 protein homolog|ventral prostate.1-like protein
|
Swissprots |
O15551
|
Accessions |
AAC78277 AAS07555 CAI29151 EAW69641 O15551 AB000714 BAA22986 AK313276 BAG36084 BC009083 BC016056 AAH16056 BM764277 DQ892211 ABM83137 EU176670 ABW03471 NM_001306 NP_001297
|
Function |
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. {ECO:0000250}.
|
Subcellular Location |
Cell junction, tight junction {ECO:0000250}. Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
Top Pathways |
Tight junction, Leukocyte transendothelial migration, Cell adhesion molecules (CAMs), Hepatitis C
|