Gene Symbol | CLDN3 |
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Entrez Gene | 1365 |
Alt Symbol | C7orf1, CPE-R2, CPETR2, HRVP1, RVP1 |
Species | Human |
Gene Type | protein-coding |
Description | claudin 3 |
Other Description | CPE-R 2|CPE-receptor 2|Clostridium perfringens enterotoxin receptor 2|claudin-3|ventral prostate.1 protein homolog|ventral prostate.1-like protein |
Swissprots | O15551 |
Accessions | AAC78277 AAS07555 CAI29151 EAW69641 O15551 AB000714 BAA22986 AK313276 BAG36084 BC009083 BC016056 AAH16056 BM764277 DQ892211 ABM83137 EU176670 ABW03471 NM_001306 NP_001297 |
Function | Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. {ECO:0000250}. |
Subcellular Location | Cell junction, tight junction {ECO:0000250}. Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Top Pathways | Tight junction, Leukocyte transendothelial migration, Cell adhesion molecules (CAMs), Hepatitis C |
claudin-3 CRISPR/Cas9 KO Plasmid (h) - sc-401756 from Santa Cruz Biotechnology
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claudin-3 HDR Plasmid (h) - sc-401756-HDR from Santa Cruz Biotechnology
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claudin-3 Double Nickase Plasmid (h) - sc-401756-NIC from Santa Cruz Biotechnology
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claudin-3 Double Nickase Plasmid (h2) - sc-401756-NIC-2 from Santa Cruz Biotechnology
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claudin-3 CRISPR Activation Plasmid (h) - sc-401756-ACT from Santa Cruz Biotechnology
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claudin-3 CRISPR Activation Plasmid (h2) - sc-401756-ACT-2 from Santa Cruz Biotechnology
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claudin-3 Lentiviral Activation Particles (h) - sc-401756-LAC from Santa Cruz Biotechnology
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claudin-3 Lentiviral Activation Particles (h2) - sc-401756-LAC-2 from Santa Cruz Biotechnology
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claudin-3 siRNA (h) - sc-43042 from Santa Cruz Biotechnology
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claudin-3 shRNA Plasmid (h) - sc-43042-SH from Santa Cruz Biotechnology
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claudin-3 shRNA (h) Lentiviral Particles - sc-43042-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN6187 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6187 from Sigma-Aldrich
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CLDN3 siRNA (Human) - CRH0955 from Cohesion Biosciences
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Claudin-3 RNAi - H00001365-R02 from Novus Biologicals
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CLDN3 - MBS8208230 from MyBioSource
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claudin-3 CRISPR/Cas9 KO Plasmid (h2) - sc-401756-KO-2 from Santa Cruz Biotechnology
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claudin-3 HDR Plasmid (h2) - sc-401756-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human CLDN3 (NM_001306.3) - SHH264785 from Creative biogene
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Human CLDN3 siRNA - orb261457 from Biorbyt
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CLDN3 shRNA Plasmid (Human) - CHH0955 from Cohesion Biosciences
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CLDN3 miRNA 3'UTR clone - MiUTR3H-05401 from Creative biogene
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