Gene Symbol |
DHX15
|
Entrez Gene |
1665
|
Alt Symbol |
DBP1, DDX15, HRH2, PRP43, PRPF43, PrPp43p
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
DEAH (Asp-Glu-Ala-His) box helicase 15
|
Other Description |
ATP-dependent RNA helicase #46|DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 15|DEAD/H box-15|DEAH (Asp-Glu-Ala-His) box polypeptide 15|DEAH box protein 15|RNA helicase 2|putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15
|
Swissprots |
Q9NQT7 O43143
|
Accessions |
EAW92814 EAW92815 EAW92816 EAW92817 EAW92818 EAW92819 EAW92820 EAW92821 O43143 AA771922 AB001636 BAA23987 AF279891 AAF90182 AK054614 AK055898 AK056726 AK303506 BAG64538 BC035974 AAH35974 BC047577 BU158645 XR_925314 NM_001358 NP_001349
|
Function |
Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA. In cooperation with TFIP11 seem to be involved in the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. {ECO:0000269|PubMed:19103666}.
|
Subcellular Location |
Nucleus. Nucleus, nucleolus.
|
Tissue Specificity |
Ubiquitous.
|
Top Pathways |
Spliceosome
|