NCAPH

Gene Symbol	NCAPH
Entrez Gene	23397
Alt Symbol	BRRN1, CAP-H
Species	Human
Gene Type	protein-coding
Description	non-SMC condensin I complex, subunit H
Other Description	barren homolog 1|chromosome-associated protein H|condensin complex subunit 2
Swissprots	B4E189 Q15003 Q8TB87
Accessions	CCQ43504 EAW71370 Q15003 AK291053 BAF83742 AK299248 BAG61279 AK303725 BAG64701 AK308050 AK310649 BC024211 AAH24211 BI559873 BI560881 D38553 BAA07556 DQ893432 ABM84358 EU176758 ABW03559 XM_005263908 XP_005263965 XM_006712388 XP_006712451 NM_001281710 NP_001268639 NM_001281711 NP_001268640 NM_001281712 NP_001268641 NM_015341 NP_056156
Function	Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. {ECO:0000269|PubMed:11136719}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:11694586}. Cytoplasm {ECO:0000269|PubMed:11694586}. Chromosome {ECO:0000269|PubMed:11694586}. Note=In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, the regulatory subunits of the complex are phosphorylated by CDK1, leading to condensin's association with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase.
Tissue Specificity	Widely expressed at low level. Expressed in proliferating cells. {ECO:0000269|PubMed:11694586}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human BRRN1 full length protein - ab161625 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human BRRN1 protein fragment - ab161626 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

NCAPH / CAP-H Antibody Blocking Peptide - LS-E6174 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NCAPH / CAP-H Antibody Blocking Peptide - LS-E16861 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NCAPH / CAP-H Antibody Blocking Peptide - LS-E16862 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NCAPH / CAP-H Antibody Blocking Peptide - LS-E26353 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human NCAPH Protein - H00023397-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human NCAPH Protein - H00023397-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

NCAPH-Antibody-Center-Blocking-Peptide - BP18809c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

BRRN1 blocking peptide - GTX89054-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

NCAPH Blocking Peptide - 33R-9135 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

NCAPH Blocking Peptide - 33R-6292 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

NCAPH Blocking Peptide - abx063767 from Abbexa Category Peptide Species Human

BRRN Peptide - AC21-1188-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

NCAPH - H00023397-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

NCAPH - H00023397-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

NCAPH - H00023397-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

NCAPH - H00023397-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

hCAP-H Peptide - 45-724P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

NCAPH fusion protein - Ag2076 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human NCAPH, GST-tagged - NCAPH-1207H from Creative Biomart Category Protein Source E.coli Species Human

NCAPH Blocking Peptide - CBP2573 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human

hCAP-H (D476) Peptide - BS3843P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Condensin complex subunit 2(NCAPH) - CSB-YP621857HU CSB-EP621857HU CSB-BP621857HU CSB-MP621857HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

HCAP-H, Peptide - MBS426201 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human

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