| Gene Symbol |
PARD6G
|
| Entrez Gene |
84552
|
| Alt Symbol |
PAR-6G, PAR6gamma
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
par-6 family cell polarity regulator gamma
|
| Other Description |
PAR-6 gamma protein|PAR6D|par-6 partitioning defective 6 homolog gamma|partitioning defective 6 homolog gamma
|
| Swissprots |
Q9BYG4 A8QM57
|
| Accessions |
CCQ43766 EAW66649 Q9BYG4 AA502508 AB043635 BAA96236 AB044556 BAB40757 AB178535 BAF92014 AB178536 BAF92015 AK128802 BC060797 AAH60797 NM_032510 NP_115899
|
| Function |
Adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions. The PARD6-PARD3 complex links GTP- bound Rho small GTPases to atypical protein kinase C proteins (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm. Cell membrane {ECO:0000250}. Cell junction, tight junction {ECO:0000250}.
|
| Tissue Specificity |
Widely expressed, with a higher expression in fetal and adult kidney.
|
| Top Pathways |
Tight junction, Endocytosis, Hippo signaling pathway, Rap1 signaling pathway
|