| Gene Symbol |
MC4R
|
| Entrez Gene |
4160
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
melanocortin 4 receptor
|
| Other Description |
MC4-R|melanocortin receptor 4
|
| Swissprots |
Q16317 B2RAC3 P32245 Q3MIJ6
|
| Accessions |
AAA35791 AAB33341 AAO92061 ABK35297 ABK35298 ABK35299 ABK35300 AFV34058 AFV34059 AFV34060 AFV34061 AFV34062 EAW63105 P32245 AK314130 BAG36820 BC069172 AAH69172 BC101802 AAI01803 BC111992 AAI11993 DA362673 NM_005912 NP_005903
|
| Function |
Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP). {ECO:0000269|PubMed:12646665}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Brain, placental, and gut tissues.
|
| Top Pathways |
Neuroactive ligand-receptor interaction
|