Gene Symbol | GIMAP5 |
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Entrez Gene | 55340 |
Alt Symbol | HIMAP3, IAN-5, IAN4, IAN4L1, IAN5, IMAP3, IROD |
Species | Human |
Gene Type | protein-coding |
Description | GTPase, IMAP family member 5 |
Other Description | GTPase IMAP family member 5|immune associated nucleotide 4 like 1|immune-associated nucleotide-binding protein 5|immunity associated protein 3|immunity-associated nucleotide 5 protein|inhibitor of radiation- and OA-induced apoptosis, Irod/Ian5 |
Swissprots | Q9NUK9 Q96F15 Q96NE4 D3DWZ5 Q6IA75 |
Accessions | EAL24486 EAW54092 EAW54093 EAW54094 Q96F15 AK002158 BAA92115 AK055568 BAB70958 AK297881 BAG60204 AL557446 AV762634 BC011732 AAH11732 BC033688 CA431916 CR457280 CAG33561 JF432844 ADZ16061 NM_018384 NP_060854 |
Function | Required for mitochondrial integrity and T-cell survival. May contribute to T-cell quiescence (By similarity). {ECO:0000250}. |
Subcellular Location | Mitochondrion outer membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}. Lysosome {ECO:0000269|PubMed:14724691, ECO:0000269|PubMed:21487483}. |
Tissue Specificity | Widely expressed with high levels in lymph node and spleen. High expression found in CD4 and CD8-positive T- cells and monocytes with very low levels in B-lymphocytes. Highly expressed in B-lymphocyte-derived neoplasms. {ECO:0000269|PubMed:14724691}. |
GIMAP5 CRISPR/Cas9 KO Plasmid (h) - sc-417843 from Santa Cruz Biotechnology
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GIMAP5 HDR Plasmid (h) - sc-417843-HDR from Santa Cruz Biotechnology
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GIMAP5 Double Nickase Plasmid (h) - sc-417843-NIC from Santa Cruz Biotechnology
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GIMAP5 Double Nickase Plasmid (h2) - sc-417843-NIC-2 from Santa Cruz Biotechnology
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GIMAP5 CRISPR Activation Plasmid (h) - sc-417843-ACT from Santa Cruz Biotechnology
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GIMAP5 CRISPR Activation Plasmid (h2) - sc-417843-ACT-2 from Santa Cruz Biotechnology
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GIMAP5 Lentiviral Activation Particles (h) - sc-417843-LAC from Santa Cruz Biotechnology
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GIMAP5 Lentiviral Activation Particles (h2) - sc-417843-LAC-2 from Santa Cruz Biotechnology
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GIMAP5 siRNA (h) - sc-89711 from Santa Cruz Biotechnology
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GIMAP5 shRNA Plasmid (h) - sc-89711-SH from Santa Cruz Biotechnology
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GIMAP5 shRNA (h) Lentiviral Particles - sc-89711-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU022191 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9286 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9286 from Sigma-Aldrich
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GIMAP5 siRNA (Human) - CRJ0671 from Cohesion Biosciences
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GIMAP5 - MBS8205460 from MyBioSource
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shRNA set against Human GIMAP5 (NM_018384.4) - SHH301078 from Creative biogene
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Human GIMAP5 siRNA - orb271172 from Biorbyt
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GIMAP5 shRNA Plasmid (Human) - CHJ0671 from Cohesion Biosciences
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GIMAP5 miRNA 3'UTR clone - MiUTR3H-09729 from Creative biogene
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