Gene Symbol | APOBEC1 |
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Entrez Gene | 339 |
Alt Symbol | APOBEC-1, BEDP, CDAR1, HEPR |
Species | Human |
Gene Type | protein-coding |
Description | apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 |
Other Description | C->U-editing enzyme APOBEC-1|apolipoprotein B mRNA editing enzyme complex-1|apolipoprotein B mRNA-editing enzyme 1 |
Swissprots | Q9UE64 Q9UM71 P41238 |
Accessions | AAD09566 BAA23882 EAW88660 EAW88661 P41238 AI380263 AI862416 BC096158 AAH96158 BC096159 BC096160 BC096161 BC101404 BC101405 BC101972 AAI01973 BC101973 AAI01974 BC144708 BC172305 AAI72305 L25877 AAA86766 L26234 AAA64230 U72890 AAD09567 U72891 AAD00185 U78720 AAD10701 NM_001304566 NP_001291495 NM_001644 NP_001635 NM_005889 NP_005880 |
Function | Catalytic component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in the APOB mRNA. Also involved in CGA (Arg) to UGA (Stop) editing in the NF1 mRNA. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation. {ECO:0000269|PubMed:11727199}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:22580899}. |
Tissue Specificity | Expressed exclusively in the small intestine. |
APOBEC1 (C-20) - sc-11738 from Santa Cruz Biotechnology
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APOBEC1 (N-15) - sc-11735 from Santa Cruz Biotechnology
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Anti-APOBEC1 antibody - ab38601 from Abcam
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Anti-APOBEC1 antibody - ab80493 from Abcam
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Anti-APOBEC1 antibody [EPR9162] - ab137104 from Abcam
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Anti-APOBEC1 Antibody (aa7-36) - LS-C98890 from LifeSpan Bioscience
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Anti-APOBEC1 Antibody - LS-C42677 from LifeSpan Bioscience
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Anti-APOBEC1 Antibody (N-Terminus, AP) - LS-C275169 from LifeSpan Bioscience
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Anti-APOBEC1 Antibody (N-Terminus, APC) - LS-C275170 from LifeSpan Bioscience
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Anti-APOBEC1 Antibody (N-Terminus, Biotin) - LS-C275171 from LifeSpan Bioscience
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Anti-APOBEC1 Antibody (N-Terminus, Azide-free, HRP) - LS-C275172 from LifeSpan Bioscience
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Anti-APOBEC1 Antibody (N-Terminus, FITC) - LS-C275173 from LifeSpan Bioscience
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Anti-APOBEC1 Antibody (N-Terminus, PE) - LS-C275174 from LifeSpan Bioscience
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Anti-APOBEC1 Antibody (N-Terminus) - LS-C326859 from LifeSpan Bioscience
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Anti-APOBEC1 Antibody (aa24-37) - LS-C87356 from LifeSpan Bioscience
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Anti-APOBEC1 Antibody (N-Terminus) - LS-C110513 from LifeSpan Bioscience
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APOBEC1 Antibody - NBP1-57268 from Novus Biologicals
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APOBEC1 Antibody - NBP1-06977 from Novus Biologicals
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APOBEC1 Antibody - H00000339-A01 from Novus Biologicals
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APOBEC1 Polyclonal Antibody - bs-12492R from Bioss
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APOBEC1 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-12492R-A350 from Bioss
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APOBEC1 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-12492R-A488 from Bioss
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APOBEC1 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-12492R-A555 from Bioss
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APOBEC1 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-12492R-A647 from Bioss
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APOBEC1 Polyclonal Antibody, Cy3 Conjugated - bs-12492R-Cy3 from Bioss
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